Weight | 428.399 g/mol |
---|---|
Formula | C15H14N2Na2O6S2 |
Hydrogen Acceptors | 8 |
Hydrogen Donors | 1 |
Aromatic Rings | 1 |
Rotatable Bonds | 5 |
Ticarpen
Ticarcillin · Ticarcillin Disodium · Ticar
74682-62-5, 29457-07-6, 4697-14-7
Score:
#426 in Microbiology
,
#3424 in Biology
,
#4276 in Chemistry
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- Vancomycin, ticarcillin, and amikacin compared with ticarcillin-clavulanate and amikacin in the empirical treatment of febrile, neutropenic children with cancer. (The New England Journal of Medicine, 1988)
- Effect of ticarcillin/potassium clavulanate on callus growth and shoot regeneration in Agrobacterium-mediated transformation of tomato (Lycopersicon esculentum Mill.) (Plant Cell Reports, 1998)
- Beta-lactamase production and susceptibilities to amoxicillin, amoxicillin-clavulanate, ticarcillin, ticarcillin-clavulanate, cefoxitin, imipenem, and metronidazole of 320 non-Bacteroides fragilis Bacteroides isolates and 129 fusobacteria from 28 U.S. centers. (Antimicrobial Agents and Chemotherapy, 1990)
- Impact of Dosing Intervals on Activity of Gentamicin and Ticarcillin Against Pseudomonas aeruginosa in Granulocytopenic Mice (The Journal of Infectious Diseases, 1983)
- In vitro synergistic properties of clavulanic acid, with ampicillin, amoxycillin and ticarcillin (Journal of Antimicrobial Chemotherapy, 1980)
- Empiric Therapy for Cancer Patients: Comparative Study of Ticarcillin-Tobramycin, Ticarcillin-Cephalothin, and Cephalothin-Tobramycin (Antimicrobial Agents and Chemotherapy, 1975)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Ticarcillin
- Ticarcillin Disodium
- Ticar
- GlaxoSmithKline Brand of Ticarcillin Disodium
- CSL Brand of Ticarcillin Disodium
- BRL 2288
- GlaxoSmithKline Brand of Ticarcillin Disodium Salt
- Tarcil
- SmithKline Beecham Brand of Ticarcillin Disodium Salt
- BRL2288
- Ticillin
- BRL-2288
- SmithKline Beecham Brand of Ticarcillin Disodium
-
SMILESCC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CSC=C3)C(=O)[O-])C(=O)[O-])C.[Na+].[Na+]
-
InChIKeyZBBCUBMBMZNEME-UHFFFAOYSA-L
- Pubchem - Ticarpen
- Wikipedia - ticarcillin disodium
Ticarcillin is a carboxypenicillin. It is almost invariably sold and used in combination with clavulanate as Timentin. Because it is a penicillin, it also falls within the larger class of beta-lactam antibiotics.
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Synthesis
Reactant
+
(2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
(Schotten-Baumann amide from acid)
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