Weight | 368.369 g/mol |
---|---|
Formula | C21H21O4P |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 3 |
Rotatable Bonds | 6 |
TRI-O-CRESYL PHOSPHATE (78-30-8)
TOCP · triorthocresyl phosphate · TOTP
Score:
#6 in Neurology
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#46 in Neuroscience
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#238 in Biology
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#248 in Chemistry
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- Hydroxylation and cyclization reactions involved in the metabolism of tri-O-cresyl phosphate (Biochemical Pharmacology, 1962)
- Biological Activity of a Tri-o-Cresyl Phosphate Metabolite. (Nature, 1961)
- THE HISTOPATHOLOGY OF TRIORTHOCRESYL PHOSPHATE POISONING: THE ETIOLOGY OF SO-CALLED GINGER PARALYSIS (THIRD REPORT) (Journal of Nervous and Mental Disease, 1931)
- Effects of tri-o-cresyl phosphate on serum estrogen and progesterone concentration and ATPase activity in the shell gland of adult hens (Chemosphere, 2000)
- THE SYSTEMIC NERVOUS AFFINITY OF TRIORTHOCRESYL PHOSPHATE (JAMAICA GINGER PALSY) (Brain, 1942)
- Anomalous phosphorylated neurofilament aggregations in central and peripheral axons of hens treated with tri-ortho-cresyl phosphate (TOCP). (Journal of Neuroscience Research, 1992)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - TOCP
- triorthocresyl phosphate
- TOTP
- triorthotolyl phosphate
- tri-2-cresyl phosphate
- tri-o-tolyl phosphate
-
SMILESCC1=CC=CC=C1OP(=O)(OC2=CC=CC=C2C)OC3=CC=CC=C3C
-
InChIKeyYSMRWXYRXBRSND-UHFFFAOYSA-N
- Pubchem - TRI-O-CRESYL PHOSPHATE
- Wikipedia - Tricresyl phosphate
Tricresyl phosphate, abbreviated TCP, is an organophosphate compound that is used as a plasticizer and diverse other applications. It is a toxic substance that causes neuropathy through ingestion, and has been the cause of several mass poisonings in history. It is a colourless, viscous liquid, although commercial samples are typically yellow.
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Areas of Application
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Alternate Names
Estimated Properties
Boiling Point | 411.34 C | EPA T.E.S.T. |
---|---|---|
Density | 1.18 g/cm3 | EPA T.E.S.T. |
Flash Point | 227.24 C | EPA T.E.S.T. |
Water Solubility | 0.43 mg/L | EPA T.E.S.T. |
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Synthesis
2-Methylbenzaldehyde
+
Reactant
(Dakin oxidation)
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