| Weight | 412.946 g/mol |
|---|---|
| Formula | C21H21ClN4OS |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 4 |
Ziprasidone (146939-27-7)
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#65 in Neuroscience
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#342 in Biology
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#360 in Chemistry
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- Ziprasidone 80 mg/day and 160 mg/day in the Acute Exacerbation of Schizophrenia and Schizoaffective Disorder: A 6-Week Placebo-Controlled Trial (Neuropsychopharmacology, 1999)
- Effectiveness of Olanzapine, Quetiapine, Risperidone, and Ziprasidone in Patients With Chronic Schizophrenia Following Discontinuation of a Previous Atypical Antipsychotic (American Journal of Psychiatry, 2006)
- Ziprasidone in the Treatment of Acute Bipolar Mania: A Three-Week, Placebo-Controlled, Double-Blind, Randomized Trial (American Journal of Psychiatry, 2003)
- Ziprasidone treatment of children and adolescents with Tourette's syndrome : A pilot study (Journal of the American Academy of Child and Adolescent Psychiatry, 2000)
- Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. (Journal of Pharmacology and Experimental Therapeutics, 1995)
- Ziprasidone: a novel antipsychotic agent with a unique human receptor binding profile (European Journal of Pharmacology, 2001)
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SMILESC1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54
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InChIKeyMVWVFYHBGMAFLY-UHFFFAOYSA-N
- Pubchem - Ziprasidone
- Wikipedia - ziprasidone
Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic which is used for the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder. Its intramuscular injection form is approved for acute agitation in people with schizophrenia. Ziprasidone is also used off-label for depression, bipolar maintenance, and post-traumatic stress disorder (PTSD).
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Estimated Properties
| Boiling Point | 373.88 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.39 g/cm3 | EPA T.E.S.T. |
| Flash Point | 307.35 C | EPA T.E.S.T. |
| Water Solubility | 2.74 mg/L | EPA T.E.S.T. |
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Ziprasidone
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