Score: #1580 in Biochemistry , #3624 in Biology , #4550 in Chemistry

  Analgesic · Antineoplastic and immunomodulating drug · Antineoplastic drug · Aromatase inhibitor · Drugs acting on the genito-urinary system · Drugs acting on the nervous system · Estrogen · Hormonal agent · Hormonal antineoplastic drug · Kappa antagonist · Opioid antagonist · Opioid receptor ligand · Opioid · Phytoestrogen · Progestogen · Psychoactive drug · Psychoactive drugs by mechanism of action · Sex hormone · Systemic hormonal preparation · Xenoestrogen

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Most-cited Publications

• Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-B Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-B Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages (Mediators of Inflammation, 2007)
• Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology (Nutrition Research, 2004)
• Plasma Kinetics and Urinary Excretion of the Flavanones Naringenin and Hesperetin in Humans after Ingestion of Orange Juice and Grapefruit Juice (Journal of Nutrition, 2001)
• In vitro inhibition of dihydropyridine oxidation and aflatoxin B1 activation in human liver microsomes by naringenin and other flavonoids. (Carcinogenesis, 1990)
• Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. (Free Radical Research, 2005)
• Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP (Journal of Lipid Research, 2001)

Areas of Application

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Trends

Alternate Names

• naringenin
• naringenin-7-sulfate
• BE-14348A
• BE 14348A
• 4',5,7-trihydroxyflavanone
• SMILES
  C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O
• InChIKey
  FTVWIRXFELQLPI-UHFFFAOYSA-N

External Links

• Pubchem - (R)-naringenin
• Wikipedia - naringenin
  Naringenin is a bitter, colourless flavanone, a type of flavonoid. It is the predominant flavanone in grapefruit, and is found in a variety of fruits and herbs.

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