| Weight | 211.859 g/mol |
|---|---|
| Formula | C3H2Cl4O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
2,2,2-Trichloroethyl chloroformate (17341-93-4)
trichloroethyl chloroformate
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- 2,2,2-trichloroethyl chloroformate: A general reagent for demethylation of tertiary methylamines (Tetrahedron Letters, 1974)
- Gas chromatography/mass spectrometry determination of amphetaminerelated drugs and ephedrines in plasma, urine and hair samples after derivatization with 2,2,2trichloroethyl chloroformate (Rapid Communications in Mass Spectrometry, 2005)
- Gas chromatographic-mass spectrometric identification and quantification of aniline after extraction from serum and derivatization with 2,2,2-trichloroethyl chloroformate, a novel derivative (Journal of Chromatography B: Biomedical Sciences and Applications, 1998)
- Determination of pethidine in plasma by electron capture gas chromatography after reaction with trichloroethyl chloroformate. (Journal of Chromatography A, 1976)
- Gas chromatography/mass spectrometry determination of mephedrone in drug seizures after derivatization with 2,2,2-trichloroethyl chloroformate. (Rapid Communications in Mass Spectrometry, 2011)
- A rapid novel derivatization of amphetamine and methamphetamine using 2,2,2-trichloroethyl chloroformate for gas chromatography electron ionization and chemical ionization mass spectrometric analysis (American Journal of Clinical Pathology, 1998)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - trichloroethyl chloroformate
-
SMILESC(C(Cl)(Cl)Cl)OC(=O)Cl
-
InChIKeyLJCZNYWLQZZIOS-UHFFFAOYSA-N
- Pubchem - 2,2,2-Trichloroethyl chloroformate
- Wikipedia - 2,2,2-Trichlorethoxycarbonyl chloride
Trichloroethyl chloroformate is used in organic synthesis for the introduction of the trichloroethyl chloroformate (Troc) protecting group for amines, thiols and alcohols. It readily cleaves vs other carbamates and can be used in an overall protecting group strategy. The troc group is traditionally removed via Zn insertion in the presence of acetic acid, resulting in elimination and decarboxylation.
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Similar Compounds
2-Chloroethyl chloroformate
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(628-12-6)
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(108-23-6)
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3 suppliers
ALLYL CHLOROFORMATE
(2937-50-0)
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ETHYL TRICHLOROACETATE
(515-84-4)
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3 suppliers
3-Chloropropyl chloroformate
(628-11-5)
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(115-20-8)
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(5912-58-3)
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Hexadecyl chloroformate
(26272-90-2)
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3 suppliers
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(55488-51-2)
2 alternate names
3 suppliers
dodecyl carbonochloridate
(24460-74-0)
2 alternate names
3 suppliers
33758-34-8
(33758-34-8)
2 alternate names
3 suppliers
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(79-22-1)
2 alternate names
4 safety hazards
3 suppliers
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(650-51-1, 76-03-9)
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4 safety hazards
3 suppliers
ACETOXYACETYL CHLORIDE
(13831-31-7)
2 alternate names
3 suppliers
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(2114-18-3)
2 alternate names
3 suppliers
DIPHOSGENE
(503-38-8)
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3 suppliers
ETHYL CHLOROACETATE
(105-39-5)
2 alternate names
6 safety hazards
3 suppliers
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(5130-24-5)
2 alternate names
3 suppliers
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(96-34-4)
2 alternate names
7 safety hazards
3 suppliers
53298-29-6
(53298-29-6)
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Chloroacetic anhydride
(541-88-8)
2 alternate names
3 suppliers
Methoxyacetyl chloride
(38870-89-2)
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3 suppliers
2-CHLOROETHYL ACRYLATE
(2206-89-5)
2 alternate names
3 suppliers
5781-53-3
(5781-53-3)
2 alternate names
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(4755-77-5)
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(76-00-6)
2 alternate names
3 suppliers
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(629-15-2)
2 alternate names
3 suppliers
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(627-42-9)
2 alternate names
3 suppliers
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(3188-13-4)
2 alternate names
3 suppliers
35976-76-2
(35976-76-2)
2 alternate names
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(3967-54-2)
2 alternate names
3 suppliers
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(105-48-6)
2 alternate names
3 safety hazards
3 suppliers
2,2'-Dichlorodiethyl ether
(111-44-4)
2 alternate names
6 safety hazards
3 suppliers
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(24468-13-1)
2 alternate names
3 suppliers
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(383-61-9)
2 alternate names
3 suppliers
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(5197-62-6)
2 alternate names
3 suppliers
638-56-2
(638-56-2)
2 alternate names
3 suppliers
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(927-68-4)
2 alternate names
3 suppliers
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(105-36-2)
2 alternate names
3 safety hazards
3 suppliers
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(50893-36-2)
2 alternate names
3 suppliers
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(56680-75-2)
2 alternate names
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(141-78-6)
2 alternate names
3 safety hazards
3 suppliers
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(77287-29-7)
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(17639-93-9)
2 alternate names
1 safety hazard
3 suppliers
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(535-13-7)
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butyl 2-chloroacetate
(590-02-3)
2 alternate names
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(52137-03-8, 628-89-7)
2 alternate names
3 suppliers
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(97-97-2)
2 alternate names
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(107-59-5)
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(19376-57-9)
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(6629-96-5)
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(18997-19-8)
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34006-60-5
(34006-60-5)
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(401-56-9)
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(111-15-9)
2 alternate names
5 safety hazards
3 suppliers
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(32718-56-2, 110-49-6)
2 alternate names
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3 suppliers
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(65071-98-9, 51901-33-8, 542-59-6)
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(16649-49-3)
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(621-62-5)
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(354-19-8)
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(623-71-2)
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(111-91-1)
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3 safety hazards
3 suppliers
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(623-51-8)
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(623-49-4)
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(96-32-2)
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3 suppliers
Methyl malonyl chloride
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decyl 2-chloroacetate
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(105-37-3)
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(81927-55-1)
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(628-66-0)
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Allyl bromoacetate
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(75-99-0)
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4 safety hazards
3 suppliers
Ethyl bromofluoroacetate
(401-55-8)
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2-(Chloromethyl)-1,3-dioxolane
(2568-30-1)
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ethyl 3-hydroxypropanoate
(623-72-3)
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3 suppliers
2,2,2-Trichloroethyl chloroformate
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