| Weight | 168.148 g/mol |
|---|---|
| Formula | C8H8O4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
3,4-Dihydroxyphenylacetic acid (102-32-9)
DOPAC · Homoprotocatechuic Acid · 3,4 Dihydroxyphenylacetic Acid
Score:
#602 in Neuroscience
,
#2710 in Biology
,
#3388 in Chemistry
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- In vivo measurement of extracellular dopamine and DOPAC in rat striatum after various dopamine-releasing drugs; implications for the origin of extracellular DOPAC. (European Journal of Pharmacology, 1988)
- In vivo electrochemical detection of catechols in the neostriatum of anaesthetized rats: dopamine or DOPAC? (Nature, 1980)
- Footshock and conditioned stress increase 3, 4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra (Brain Research, 1985)
- Simultaneous determination of 3,4-dihydroxyphenylalanine, 5-hydroxytryptophan, dopamine, 4-hydroxy-3-methoxyphenylalanine, norepinephrine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, serotonin, and 5-hydroxyindoleacetic acid in rat cerebrospinal fluid and brain by high-performance liquid chromatography with electrochemical detection. (Journal of Neurochemistry, 1982)
- Stress-induced increase in 3,4-dihydroxyphenylacetic acid (DOPAC) levels in the cerebral cortex and in n. accumbens: reversal by diazepam. (Life Sciences, 1978)
- Simultaneous determination of dopamine, DOPAC and homovanillic acid. Direct injection of supernatants from brain tissue homogenates in a liquid chromatography--electrochemical detection system. (Journal of Chromatography B: Biomedical Sciences and Applications, 1980)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - DOPAC
- Homoprotocatechuic Acid
- 3,4 Dihydroxyphenylacetic Acid
- 3,4-Dihydroxyphenylacetic Acid, Monosodium Salt
-
SMILESC1=CC(=C(C=C1CC(=O)O)O)O
-
InChIKeyCFFZDZCDUFSOFZ-UHFFFAOYSA-N
- Pubchem - 3,4-Dihydroxyphenylacetic acid
- Wikipedia - 3,4-Dihydroxyphenylacetic acid
3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
Similar Compounds
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3,4-Dihydroxyphenylacetic acid
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