| Weight | 129.094 g/mol |
|---|---|
| Formula | C4H4FN3O |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 0 |
5-Fluorocytosine (2022-85-7)
Flucytosine · Ancobon · Ancotil
Score:
#183 in Microbiology
,
#1890 in Biology
,
#2278 in Chemistry
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- A Comparison of Amphotericin B Alone and Combined with Flucytosine in the Treatment of Cryptoccal Meningitis (The New England Journal of Medicine, 1979)
- Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system (Proceedings of the National Academy of Sciences of the United States of America, 1992)
- Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase (Proceedings of the National Academy of Sciences of the United States of America, 1994)
- Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions (Journal of Antimicrobial Chemotherapy, 2000)
- Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks. (The New England Journal of Medicine, 1987)
- In Vivo Antitumor Activity of 5-Fluorocytosine on Human Colorectal Carcinoma Cells Genetically Modified to Express Cytosine Deaminase (Cancer Research, 1993)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Flucytosine
- Ancobon
- Ancotil
- Allphar Brand of Flucytosine
- Alcobon
- ICN Pharmaceuticals Brand of Flucytosine
- Dermatech Brand of Flucytosine
- Roche Brand of Flucytosine
- CSP Brand of Flucytosine
-
SMILESC1=NC(=O)NC(=C1F)N
-
InChIKeyXRECTZIEBJDKEO-UHFFFAOYSA-N
- Pubchem - 5-Fluorocytosine
- Wikipedia - flucytosine
Flucytosine, also known as 5-fluorocytosine (5-FC), is an antifungal medication. It is specifically used, together with amphotericin B, for serious Candida infections and cryptococcosis. It may be used by itself or with other antifungals for chromomycosis.
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5-Fluorocytosine
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