| Weight | 192.517 g/mol |
|---|---|
| Formula | C5H12Cl3N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
55-86-7 (55-86-7)
Nitrogen Mustard · Mechlorethamine · Mustargen
Score:
#1274 in Biology
,
#1474 in Chemistry
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- Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide (Journal of Chronic Diseases, 1960)
- Nitrogen Mustard Therapy: Use of Methyl-Bis(Beta-Chloroethyl)amine Hydrochloride and Tris(Beta-Chloroethyl)amine Hydrochloride for Hodgkin's Disease, Lymphosarcoma, Leukemia and Certain Allied and Miscellaneous Disorders (JAMA, 1946)
- Mechanism by which caffeine potentiates lethality of nitrogen mustard. (Proceedings of the National Academy of Sciences of the United States of America, 1982)
- Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis (Cancer Research, 1993)
- Long-term efficacy, curative potential, and carcinogenicity of topical mechlorethamine chemotherapy in cutaneous T cell lymphoma. (Journal of The American Academy of Dermatology, 1989)
- The initial clinical trial of nitrogen mustard (American Journal of Surgery, 1963)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Nitrogen Mustard
- Mechlorethamine
- Mustargen
- Mechlorethamine Hydrochloride
- Mustine
- Nitromin
- Mechlorethamine Hydrochloride N-Oxide
- NSC 10107
- Mechlorethamine Hydrochloride N Oxide
- NSC 762
- Bis(2-chloroethyl)methylamine
- Chlorethazine
- NSC10107
- NSC762
- Chlormethine
- Nitrogen Mustard N-Oxide
- Methylchlorethamine
- Caryolysine
- NSC-762
- Embichin
- Mechlorethamine Oxide
- Mechlorethamine N Oxide
- Mechlorethamine N-Oxide
- Nitrogranulogen
- NSC-10107
- Mitomen
- Nitrogen Mustard N Oxide
- Cloramin
-
SMILESCN(CCCl)CCCl.Cl
-
InChIKeyQZIQJVCYUQZDIR-UHFFFAOYSA-N
- Pubchem - 55-86-7
- Wikipedia - mechlorethamine hydrochloride
Chlormethine (INN, BAN), also known as mechlorethamine (USAN, USP), mustine, HN2, and (in post-Soviet states) Embichin (), is a nitrogen mustard sold under the brand name Mustargen. It is the prototype of alkylating agents, a group of anticancer chemotherapeutic drugs. It works by binding to DNA, crosslinking two strands and preventing cell duplication.
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Similar Compounds
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4584-49-0
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(2746-07-8)
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(1932-03-2)
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(2008-75-5)
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(2315-36-8)
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(13435-20-6)
29 alternate names
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10052-47-8
(10052-47-8)
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TETRAETHYLAMMONIUM CHLORIDE
(56-34-8)
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Tetraethylammonium iodide
(68-05-3)
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(2700-16-5)
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TETRAETHYLAMMONIUM BROMIDE
(71-91-0)
29 alternate names
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994-29-6
(994-29-6)
29 alternate names
3 suppliers
2-Chloro-N,N-dimethylacetamide
(2675-89-0)
29 alternate names
3 suppliers
N,N-DIMETHYLETHYLAMINE
(598-56-1, 70955-13-4)
29 alternate names
4 safety hazards
3 suppliers
N-(2-Chloroethyl)acetamide
(7355-58-0)
29 alternate names
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Diethylcyanamide
(617-83-4)
29 alternate names
3 suppliers
(3-CHLOROPROPYL)ETHYL(METHYL)AMINE HYDROCHLORIDE
(1609401-32-2)
29 alternate names
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1-(2-chloro-1-methylethyl)pyrrolidine hydrochloride
(322391-26-4)
29 alternate names
3 suppliers
2-chloro-N-(2-chloroethyl)acetamide
(13627-28-6)
29 alternate names
3 suppliers
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(100-36-7)
29 alternate names
2 safety hazards
3 suppliers
5407-04-5
(5407-04-5)
29 alternate names
3 suppliers
109-54-6
(109-54-6)
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104-77-8
(104-77-8)
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(104-77-8)
29 alternate names
3 suppliers
2-Chloro-N-ethylacetamide
(105-35-1)
29 alternate names
3 suppliers
N,N-Diisopropylmethylamine
(10342-97-9)
29 alternate names
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2-chloro-N-isopropyl-N-methylacetamide
(39086-71-0)
29 alternate names
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Tris(2-aminoethyl)amine
(4097-89-6, 14350-52-8)
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(120-94-5)
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(10138-93-9, 35365-94-7)
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(3424-21-3)
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(1942-52-5, 100-38-9)
29 alternate names
3 suppliers
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(429-06-1)
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3 suppliers
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(100-37-8)
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7 safety hazards
3 suppliers
1069-72-3
(1069-72-3)
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(100-38-9)
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TRIPROPYLAMINE
(102-69-2)
29 alternate names
4 safety hazards
3 suppliers
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(105-59-9)
29 alternate names
3 safety hazards
3 suppliers
N-ethyl-N,N'-dimethyl-1,2-ethanediamine
(98279-30-2)
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2-Chloro-N-methylacetamide
(96-30-0)
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Diethylamine N-d1
(997-11-5)
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(660-68-4)
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2-Chloroethylamine hydrochloride
(870-24-6)
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2-CHLORO-N,N-DIPROPYLACETAMIDE
(2315-37-9)
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(108-00-9)
29 alternate names
2 safety hazards
3 suppliers
Dimethylaminoacetonitrile
(926-64-7, 3976-11-2)
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3030-47-5
(3030-47-5)
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N,N,N'-Triethylethylenediamine
(105-04-4)
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Tetraethylammonium nitrate
(1941-26-0)
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33451-85-3
(33451-85-3)
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(106-58-1)
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1-Methylpiperazine
(109-01-3)
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N,N-Diethyl-N'-methylethylenediamine
(104-79-0)
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N,N,N',N'-Tetraethylethylenediamine
(150-77-6)
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1,4,7-Trimethyl-1,4,7-triazonane
(96556-05-7)
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4-(2-CHLORO-1-METHYLETHYL)MORPHOLINE
(76191-26-9)
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1-(chloroacetyl)-4-methylpiperazine hydrochloride
(42951-91-7)
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1,4-Bis(chloroacetyl)piperazine
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565165-44-8
(565165-44-8)
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33527-91-2
(33527-91-2)
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1-Ethylpiperazine
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(2895-21-8)
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16873-13-5
(16873-13-5)
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1,4-Diazabicyclo[2.2.2]octane
(280-57-9)
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3 safety hazards
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Triethylamine N-oxide
(2687-45-8)
29 alternate names
3 suppliers
N,N-Dimethyl-N'-ethylethylenediamine
(123-83-1)
29 alternate names
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2-chloro-n-prop-2-ynylacetamide
(7458-03-9)
29 alternate names
3 suppliers
36421-15-5
(36421-15-5)
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N,N-Dimethylallylamine
(2155-94-4)
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N-Methyldibutylamine
(3405-45-6)
29 alternate names
3 suppliers
140-31-8
(28631-79-0, 140-31-8)
29 alternate names
7 safety hazards
3 suppliers
N-methyl-2-(4-methylpiperazin-1-yl)ethanamine
(98545-15-4)
29 alternate names
3 suppliers
2-(4-methylpiperazin-1-yl)ethanamine
(934-98-5)
29 alternate names
3 suppliers
N,N-Bis(3-aminopropyl)methylamine
(105-83-9, 11071-12-8)
29 alternate names
2 safety hazards
3 suppliers
55-86-7
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