| Weight | 152.182 g/mol |
|---|---|
| Formula | C5H4N4S |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 0 |
6-Mercaptopurine (50-44-2)
Mercaptopurine · Purinethol · 6 Mercaptopurine
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#386 in Physics
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#1027 in Biology
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#1145 in Chemistry
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- Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. (American Journal of Human Genetics, 1980)
- Treatment of Crohn's disease with 6-mercaptopurine. A long-term, randomized, double-blind study. (The New England Journal of Medicine, 1980)
- Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease (Gastroenterology, 2000)
- Azathioprine and 6-mercaptopurine in Crohn disease. A meta-analysis. (Annals of Internal Medicine, 1995)
- Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance (Annals of Internal Medicine, 1997)
- 6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity. (Annals of Internal Medicine, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - H412: Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard - Category 3 - Mercaptopurine
- Purinethol
- 6 Mercaptopurine
- Mercaptopurina Wellcome
- 6-Thiohypoxanthine
- BW 57-323H
- BW 57 323H
- Puri-Nethol
- Puri Nethol
- Mecaptopurine Anhydrous
- 1,7-Dihydro-6H-purine-6-thione
- 6 Thiohypoxanthine
- Leupurin
- 6-Mercaptopurine Monohydrate
- BW 57323H
- 6-Thiopurine
- 6 Thiopurine
- 6 Mercaptopurine Monohydrate
- Purimethol
-
SMILESC1=NC2=C(N1)C(=S)N=CN2
-
InChIKeyGLVAUDGFNGKCSF-UHFFFAOYSA-N
- Pubchem - 6-Mercaptopurine
- Wikipedia - mercaptopurine anhydrous
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis. For ALL it is generally used with methotrexate.
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6-Mercaptopurine
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