Weight | 279.295 g/mol |
---|---|
Formula | C17H13NO3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 3 |
A-Phthalimidopropiophenone (19437-20-8)
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SMILESCC(C(=O)C1=CC=CC=C1)N2C(=O)C3=CC=CC=C3C2=O
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InChIKeyCKLKGWHINGNHOK-UHFFFAOYSA-N
- Pubchem - A-Phthalimidopropiophenone
- Wikipedia - Phthalimidopropiophenone
Phthalimidopropiophenone is a chemical intermediate used in the synthesis of cathinone. It has been found to be sold on the illicit market as a controlled substance analogue, but little is currently known about its pharmacology or toxicology. Phthalimidopropiophenone is not an active stimulant, but is believed to be potentially capable of acting as a prodrug for cathinone when ingested, as similar N-substituted cathinone derivatives have been encountered by law enforcement, and were found to form cathinone in vivo by initial hydroxylation of the pyrrolidine ring followed by subsequent dehydrogenation to the corresponding lactam, then by double dealkylation of the pyrrolidine ring to form the primary amine.
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Reactant
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CHLOROBENZENE
(Grignard carbonyl)
117886-88-1
+
Reactant
(Schotten-Baumann amide from acid)
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