| Weight | 173.128 g/mol |
|---|---|
| Formula | C5H7N3O4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
azaserine (115-02-6)
Azeserine · O Diazoacetyl L serine · O-Diazoacetyl-L-serine
Score:
#553 in Biochemistry
,
#1669 in Biology
,
#1967 in Chemistry
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- Sigma-Aldrich - azaserine18.90 - 632.00 USD
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- Adenocarcinoma of the Pancreas in Azaserine-treated Rats (Cancer Research, 1975)
- Pancreatic carcinoma in azaserine-treated rats: Induction, classification and dietary modulation of incidence (Cancer, 1981)
- Transplantation of azaserine-induced carcinomas of pancreas in rats* (Cancer Letters, 1979)
- Dietary Modulation of Azaserine-induced Pancreatic Carcinogenesis in the Rat (Cancer Research, 1981)
- Promotion by Unsaturated Fat of Azaserine-induced Pancreatic Carcinogenesis in the Rat (Cancer Research, 1981)
- Involvement of Atp, 5-Phosphoribosyl-Pyrophosphate and L-Azaserine in the Enzymatic Formation of Glycinamide Ribotide Intermediates in Inosinic Acid Biosynthesis (Journal of the American Chemical Society, 1955)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - Azeserine
- O Diazoacetyl L serine
- O-Diazoacetyl-L-serine
- LL-D05139a
-
SMILESC(C(C(=O)O)N)OC(=C[N+]#N)[O-]
-
InChIKeyAGNGYMCLFWQVGX-UHFFFAOYSA-N
- Pubchem - azaserine
- Wikipedia - Azaserine
Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic and antibiotic properties deriving from its action as a purinergic antagonist and structural similarity to glutamine. Azazerine acts by competitively inhibiting glutamine amidotransferase, a key enzyme responsible for glutamine metabolism.
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azaserine
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