| Weight | 132.119 g/mol |
|---|---|
| Formula | C4H8N2O3 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
MAM acetate (592-62-1)
Methylazoxymethanol Acetate · (Methyl-ONN-azoxy)methanol Acetate
Score:
#526 in Neuroscience
,
#2422 in Biology
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- A Neurobehavioral Systems Analysis of Adult Rats Exposed to Methylazoxymethanol Acetate on E17: Implications for the Neuropathology of Schizophrenia (Biological Psychiatry, 2006)
- Inhibitory effects of selenium on 1,2-dimethylhydrazine and methylazoxymethanol acetate induction of colon tumors. (Cancer Letters, 1977)
- Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. (Behavioural Brain Research, 2009)
- Effect of high-fat diet on colon carcinogenesis in F344 rats treated with 1,2-dimethylhydrazine, methylazoxymethanol acetate, or methylnitrosourea. (Cancer Research, 1977)
- Ontogeny of Neurochemical Markers for Noradrenergic, GABAergic and Cholinergic Neurons in Neocortex Lesioned with Methylazoxymethanol Acetate (Journal of Neurochemistry, 1980)
- Inhibitory effect of chlorogenic acid on methylazoxymethanol acetate-induced carcinogenesis in large intestine and liver of hamsters (Cancer Letters, 1986)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H351: Suspected of causing cancer
Warning Carcinogenicity - Category 2 - Methylazoxymethanol Acetate
- (Methyl-ONN-azoxy)methanol Acetate
-
SMILESCC(=O)OCN=[N+](C)[O-]
-
InChIKeyBELPJCDYWUCHKF-UHFFFAOYSA-N
- Pubchem - MAM acetate
- Wikipedia - methylazoxymethanol acetate
Methylazoxymethanol acetate, MAM, is a neurotoxin which reduces DNA synthesis used in making animal models of neurological diseases including schizophrenia and epilepsy. MAM is found in cycad seeds, and causes zamia staggers. It selectively targets neuroblasts in the central nervous system.
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