| Weight | 260.253 g/mol |
|---|---|
| Formula | C12H12N4O3 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
BENZNIDAZOLE (22994-85-0)
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#474 in Microbiology
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#1654 in Biochemistry
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#3731 in Biology
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#4698 in Chemistry
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- Long-Term Cardiac Outcomes of Treating Chronic Chagas Disease with Benznidazole versus No Treatment: A Nonrandomized Trial (Annals of Internal Medicine, 2006)
- Randomised trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection (The Lancet, 1996)
- Treatment of chronic Chagas' disease with benznidazole: Clinical and serologic evolution of patients with long-term follow-up (American Heart Journal, 1994)
- Efficacy of chemotherapy with benznidazole in children in the indeterminate phase of Chagas' disease (American Journal of Tropical Medicine and Hygiene, 1998)
- Long term evaluation of etiological treatment of Chagas disease with benznidazole (Revista Do Instituto De Medicina Tropical De Sao Paulo, 2002)
- A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes (Proceedings of the National Academy of Sciences of the United States of America, 2008)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC1=CC=C(C=C1)CNC(=O)CN2C=CN=C2[N+](=O)[O-]
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- Wikipedia - benznidazole
Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. While it is highly effective in early disease this decreases in those who have long term infection. It is the first line treatment given its moderate side effects compared to nifurtimox.
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