Weight | 336.367 g/mol |
---|---|
Formula | C20H18NO4+ |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 0 |
Aromatic Rings | 3 |
Rotatable Bonds | 2 |
berberine (2086-83-1, 4263-84-7)
Umbellatine
Score:
#1596 in Biochemistry
,
#3652 in Biology
,
#4582 in Chemistry
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- Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. (Nature Medicine, 2004)
- Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States (Diabetes, 2006)
- Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5-methoxyhydnocarpin, a multidrug pump inhibitor (Proceedings of the National Academy of Sciences of the United States of America, 2000)
- The anti-inflammatory potential of berberine in vitro and in vivo (Cancer Letters, 2004)
- Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores (Phytochemistry, 1997)
- A berberine-aniline blue fluorescent staining procedure for suberin, lignin, and callose in plant tissue (Protoplasma, 1988)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Umbellatine
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SMILESCOC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC
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InChIKeyYBHILYKTIRIUTE-UHFFFAOYSA-N
- Pubchem - berberine
- Wikipedia - Berberine
Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as Berberis (e.g. Berberis vulgaris - barberry, Berberis aristata - tree turmeric, Mahonia aquifolium - Oregon-grape, Hydrastis canadensis - goldenseal, Xanthorhiza simplicissima - yellowroot, Phellodendron amurense - Amur cork tree, Coptis chinensis - Chinese goldthread, Tinospora cordifolia, Argemone mexicana - prickly poppy, and Eschscholzia californica - Californian poppy. Berberine is usually found in the roots, rhizomes, stems, and bark.
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