Weight | 246.306 g/mol |
---|---|
Formula | C6H14O6S2 |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 7 |
busulfan (55-98-1)
Myleran · Busulphan · Busulfex
Score:
#134 in Biochemistry
,
#584 in Biology
,
#621 in Chemistry
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- Sigma-Aldrich - busulfan28.10 - 168.00 USD
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- Marrow Transplantation for Acute Nonlymphocytic Leukemia after Treatment with Busulfan and Cyclophosphamide (The New England Journal of Medicine, 1983)
- Pregnancies following high-dose cyclophosphamide with or without high- dose busulfan or total-body irradiation and bone marrow transplantation (Blood, 1996)
- Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen (Blood, 1987)
- Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group [see comments] (Blood, 1994)
- Pharmacokinetics of busulfan: correlation with veno-occlusive disease in patients undergoing bone marrow transplantation (Cancer Chemotherapy and Pharmacology, 1989)
- Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide (Blood, 1994)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H301: Toxic if swallowed
Danger Acute toxicity, oral - Category 3 - H350: May cause cancer
Danger Carcinogenicity - Category 1A, 1B - H371: May cause damage to organs
Warning Specific target organ toxicity, single exposure - Category 2 - Myleran
- Busulphan
- Busulfex
- Mylran
- Busulfan Wellcome
- Mylecytan
- Glyzophrol
- n-Butane-1,3-di(methylsulfonate)
- Myelosan
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SMILESCS(=O)(=O)OCCCCOS(=O)(=O)C
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InChIKeyCOVZYZSDYWQREU-UHFFFAOYSA-N
- Pubchem - busulfan
- Wikipedia - busulfan
Busulfan (Myleran, GlaxoSmithKline, Busulfex IV, Otsuka America Pharmaceutical, Inc.) is a cancer drug, in use since 1959. Busulfan is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation is 1,4-butanediol dimethanesulfonate.
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