| Weight | 224.149 g/mol |
|---|---|
| Formula | C7H13O6P |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 5 |
mevinphos (7786-34-7, 298-01-1)
Phosdrin · Fosdrin · Fosdrine
Score:
#113 in Neuroscience
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#131 in Biochemistry
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#573 in Biology
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#609 in Chemistry
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- CYTOLOGICAL EFFECTS OF THE PESTICIDES PHOSDRIN AND BLADEX ON TRADESCANTIA AND VICIA FABA (Canadian journal of genetics and cytology, 1972)
- Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat (Neuropharmacology, 2004)
- Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by NOS I and II isoforms (Neuropharmacology, 2005)
- Spectral changes in systemic arterial pressure signals during acute mevinphos intoxication in the rat. (Shock, 2001)
- Coenzyme Q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat (Shock, 2005)
- EXPOSURE OF SPRAYERS AND PLANT HANDLERS TO MEVINPHOS IN FINNISH GREENHOUSES (American Industrial Hygiene Association Journal, 1993)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H227: Combustible liquid
Warning Flammable liquids - Category 4 - H300: Fatal if swallowed
Danger Acute toxicity, oral - Category 1, 2 - H310: Fatal in contact with skin
Danger Acute toxicity, dermal - Category 1, 2 - H370: Causes damage to organs
Danger Specific target organ toxicity, single exposure - Category 1 - H400: Very toxic to aquatic life
Warning Hazardous to the aquatic environment, acute hazard - Category 1 - H410: Very toxic to aquatic life with long lasting effects
Warning Hazardous to the aquatic environment, long-term hazard - Category 1 - Phosdrin
- Fosdrin
- Fosdrine
-
SMILESCC(=CC(=O)OC)OP(=O)(OC)OC
-
InChIKeyGEPDYQSQVLXLEU-UHFFFAOYSA-N
- Pubchem - mevinphos
- Wikipedia - (E)-mevinphos
Mevinphos is an organophosphate insecticide that acts as an acetylcholinesterase inhibitor to control insects in a wide range of crops. It is most commonly used for the control of chewing and sucking insects, as well as spider mites.
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Synthesis
Reactant
+
1-Hydroxy-1,2-benziodoxol-3(1H)-one 1-oxide
(Nicolaou IBX dehydrogenation)
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mevinphos
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