| Weight | 406.482 g/mol |
|---|---|
| Formula | C24H26N2O4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 4 |
| Rotatable Bonds | 10 |
carvedilol (72956-09-3)
Coreg · Kredex · BM-14190
Score:
#79 in Biochemistry
,
#349 in Biology
,
#368 in Chemistry
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- Sigma-Aldrich - carvedilol64.60 - 514.50 USD
- Fisher Scientific - Search for carvedilol
- TCI - carvedilol107.00 - 386.00 USD
- The effect of carvedilol on morbidity and mortality in patients with chronic heart failure (The New England Journal of Medicine, 1996)
- The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure (Acc Current Journal Review, 2009)
- Effect of carvedilol on survival in severe chronic heart failure (The New England Journal of Medicine, 2001)
- Comparison of carvedilol and metoprolol on clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol European Trial (COMET): randomised controlled trial. (The Lancet, 2003)
- Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial. (The Lancet, 2001)
- Carvedilol Produces Dose-Related Improvements in Left Ventricular Function and Survival in Subjects With Chronic Heart Failure (Circulation, 1996)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Coreg
- Kredex
- BM-14190
- Eucardic
- Coropres
- carvedilol hydrochloride
- BM 14190
- carvedilol, (S)-isomer
- carvedilol, (R)-isomer
- carvedilol, 14C-labeled
- Querto
- Dilatrend
- carvedilol, (+-)-isomer
-
SMILESCOC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
-
InChIKeyOGHNVEJMJSYVRP-UHFFFAOYSA-N
- Pubchem - carvedilol
- Wikipedia - carvedilol
Carvedilol, sold under the brand name Coreg among others, is a beta blocker used for treating mild to severe congestive heart failure (CHF), left ventricular dysfunction (LVD) following heart attack in people who are otherwise stable, and for treating high blood pressure. Beta blockers block the beta receptors on heart muscle and other cells, making them more relaxed and less responsive to stress hormones. Carvedilol also blocks alpha receptors, which are found on blood vessels, and relaxes the blood vessels, dilating them, which lowers blood pressure and vascular resistance.
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Most-cited Publications
Areas of Application
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Alternate Names
External Links
Synthesis
1-amino-3-(9H-carbazol-4-yloxy)-propan-2-ol
+
1-(2-chloroethoxy)-2-methoxybenzene
(Alkylation of primary amines)
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carvedilol
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