Weight | 462.513 g/mol |
---|---|
Formula | C18H18N6O5S2 |
Hydrogen Acceptors | 10 |
Hydrogen Donors | 3 |
Aromatic Rings | 2 |
Rotatable Bonds | 7 |
cefamandole (34444-01-4)
Cephamandole · Compound 83405
Score:
#347 in Microbiology
,
#2834 in Biology
,
#3548 in Chemistry
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- Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens (Infection, 1983)
- A randomized study of carbenicillin plus cefamandole or tobramycin in the treatment of febrile episodes in cancer patients (The American Journal of Medicine, 1979)
- Efficacy of cefazolin, cefamandole, and gentamicin as prophylactic agents in cardiac surgery. Results of a prospective, randomized, double-blind trial in 1030 patients. (Annals of Surgery, 1987)
- Synergistic Activity of Dispersin B and Cefamandole Nafate in Inhibition of Staphylococcal Biofilm Growth on Polyurethanes (Antimicrobial Agents and Chemotherapy, 2007)
- Emergence of Resistance to Cefamandole: Possible Role of Cefoxitin-Inducible Beta-Lactamases (Antimicrobial Agents and Chemotherapy, 1979)
- Comparative study of cefazolin, cefamandole, and vancomycin for surgical prophylaxis in cardiac and vascular operations. A double-blind randomized trial. (The Journal of Thoracic and Cardiovascular Surgery, 1992)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Cephamandole
- Compound 83405
-
SMILESCN1C(=NN=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(C4=CC=CC=C4)O)SC2)C(=O)O
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InChIKeyOLVCFLKTBJRLHI-UHFFFAOYSA-N
- Pubchem - cefamandole
- Wikipedia - cefamandole
Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally. Cefamandole is no longer available in the United States.
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