CHLOROACETALDEHYDE (107-20-0)

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Suppliers

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  250 g
  $375.00

  1 kg
  $550.00

Most-cited Publications

• Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse (Toxicological Sciences, 1992)
• Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide. (Proceedings of the National Academy of Sciences of the United States of America, 1975)
• Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol (Biochemical and Biophysical Research Communications, 1975)
• The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride (Chemico-Biological Interactions, 1976)
• All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylase. (Proceedings of the National Academy of Sciences of the United States of America, 1994)
• Activation of vinyl chloride to covalently bound metabolites: roles of 2-chloroethylene oxide and 2-chloroacetaldehyde. (Biochemistry, 1979)

Areas of Application

Safety

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  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
• H227: Combustible liquid
  Warning Flammable liquids - Category 4
• H301: Toxic if swallowed
  Danger Acute toxicity, oral - Category 3
• H310: Fatal in contact with skin
  Danger Acute toxicity, dermal - Category 1, 2
• H314: Causes severe skin burns and eye damage
  Danger Skin corrosion/irritation - Category 1A, B, C
• H318: Causes serious eye damage
  Danger Serious eye damage/eye irritation - Category 1
• H351: Suspected of causing cancer
  Warning Carcinogenicity - Category 2
• H373: Causes damage to organs through prolonged or repeated exposure
  Warning Specific target organ toxicity, repeated exposure - Category 2
• H411: Toxic to aquatic life with long lasting effects
  Hazardous to the aquatic environment, long-term hazard - Category 2

Trends

Alternate Names

• 2-chloroacetaldehyde
• chloroacetaldehyde hydrate
• SMILES
  C(C=O)Cl
• InChIKey
  QSKPIOLLBIHNAC-UHFFFAOYSA-N

External Links

• Pubchem - CHLOROACETALDEHYDE
• Wikipedia - chloroacetaldehyde
  Chloroacetaldehyde is the organic compound with the formula ClCH2CHO. Like some related compounds, it is highly electrophilic reagent and a potentially dangerous alkylating agent. The compound is not normally encountered in the anhydrous form, but rather as the hydrate (acetal), ClCH2CH(OH)2.

Synthesis

2-chloroethanol  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)

Synthesis of CHLOROACETALDEHYDE ›

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2-Chloroacetamide (79-07-2)

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chloroacetic acid (79-11-8)

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2-CHLOROMALONALDEHYDE (36437-19-1)

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3-CHLOROPROPANAL (19434-65-2)

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GLYOXAL (107-22-2, 40094-65-3)

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FLUOROACETYL CHLORIDE (359-06-8)

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1-CHLOROPROPANE (26446-76-4, 540-54-5)

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2-CHLOROPROPANE (75-29-6)

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2,2-Dichloroacetamide (683-72-7)

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CHLOROACETONITRILE (107-14-2)

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2-Chloro-N-methylacetamide (96-30-0)

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2-Chloroethylamine hydrochloride (870-24-6)

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1-BROMO-2-CHLOROETHANE (107-04-0)

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4-Chloro-2-butanone (6322-49-2)

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METHYL CHLOROACETATE (96-34-4)

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1-Chloro-2-fluoroethane (762-50-5)

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1-Chloro-2-iodoethane (624-70-4)

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3-Chloropropionyl chloride (625-36-5)

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2-chloroethanol (107-07-3)

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ALLYL CHLORIDE (107-05-1)

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Propargyl chloride (624-65-7)

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1,1,3-TRICHLOROACETONE (921-03-9)

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1,4-Dichlorobutan-2-one (16714-78-6)

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Isobutyryl chloride (79-30-1)

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TRICHLOROACETYL CHLORIDE (76-02-8)

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3-CHLORO-1-PROPANOL (627-30-5)

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acetate (64-19-7, 71-50-1)

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ACETYL BROMIDE (506-96-7)

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Cobalt(II) acetate (71-48-7, 6147-53-1, 71-48-7, 5931-89-5)

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Potassium acetate (127-08-2)

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Dirhodium tetraacetate (15956-28-2)

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Barium acetate (543-80-6)

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(2H9)-tert-Butyl chloride (918-20-7)

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Iron(II) acetate (3094-87-9)

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Palladium(II) acetate (19807-27-3, 3375-31-3)

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2-Chloropropene (557-98-2)

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1-Chloro-1-fluoroethane (1615-75-4, 110587-14-9)

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29617-66-1 (29617-66-1, 28554-00-9)

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butyraldehyde (123-72-8)

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ACETYL FLUORIDE (557-99-3)

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ISOBUTYRALDEHYDE (78-84-2)

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3-Chloropropanoic acid (107-94-8)

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1-Chloro-1,2-difluoroethane (338-64-7)

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chlorofluoroacetic acid (471-44-3)

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TRICHLOROACETIC ACID (650-51-1, 76-03-9)

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Methoxyacetyl chloride (38870-89-2)

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1-chlorohexan-2-one (20261-68-1)

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1-Chloro-3-iodopropane (6940-76-7)

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3-Chloropropionitrile (542-76-7)

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ETHYL CHLOROACETATE (105-39-5)

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Propionyl fluoride (430-71-7)

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CHLOROACETALDEHYDE

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