Weight | 230.098 g/mol |
---|---|
Formula | C9H9Cl2N3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 1 |
clonidine (4205-90-7)
Catapres · Clonidine Hydrochloride · Dixarit
Score:
#133 in Neuroscience
,
#650 in Biology
,
#695 in Chemistry
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- Inhibition of both noradrenergic and serotonergic neurons in brain by the -adrenergic agonist clonidine (Brain Research, 1975)
- Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. (Nature, 1978)
- Distribution of 2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents (Brain Research Reviews, 1984)
- alpha(2)-adrenergic agonists for regional anesthesia - A clinical review of clonidine (1984-1995) (Anesthesiology, 1996)
- CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS (The Lancet, 1978)
- Agmatine: An endogenous clonidine-displacing substance in the brain (Science, 1994)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Catapres
- Clonidine Hydrochloride
- Dixarit
- ST 155
- Catapresan
- Catapressan
- Gemiton
- Clofelin
- Clofenil
- M 5041T
- Hemiton
- ST155
- M-5041T
- Isoglaucon
- Klofelin
- Clopheline
- Clonidine Dihydrochloride
- M5041T
- Clonidine Monohydrochloride
- Boehringer Ingelheim Brand of Clonidine Hydrochloride
- Chlophazolin
- Klofenil
- ST-155
- Clonidine Monohydrobromide
-
SMILESC1CN=C(N1)NC2=C(C=CC=C2Cl)Cl
-
InChIKeyGJSURZIOUXUGAL-UHFFFAOYSA-N
- Pubchem - clonidine
- Wikipedia - clonidine
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. It is classified as a centrally acting 2 adrenergic agonist and imidazoline receptor agonist that has been in clinical use since 1966.
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Estimated Properties
Density | 1.5 g/cm3 | EPA T.E.S.T. |
---|---|---|
Flash Point | 162.44 C | EPA T.E.S.T. |
Water Solubility | 193.34 mg/L | EPA T.E.S.T. |
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Synthesis
39075-79-1
+
Reactant
(Alkylation of primary amines)
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