| Weight | 266.559 g/mol |
|---|---|
| Formula | C9H10Cl3N3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
CLONIDINE HYDROCHLORIDE (4205-91-8)
Clonidine · Catapres · Dixarit
Score:
#607 in Neuroscience
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#2731 in Biology
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#3423 in Chemistry
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- Inhibition of both noradrenergic and serotonergic neurons in brain by the -adrenergic agonist clonidine (Brain Research, 1975)
- Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine. (Nature, 1978)
- Distribution of 2 agonist binding sites in the rat and human central nervous system: Analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents (Brain Research Reviews, 1984)
- alpha(2)-adrenergic agonists for regional anesthesia - A clinical review of clonidine (1984-1995) (Anesthesiology, 1996)
- CLONIDINE BLOCKS ACUTE OPIATE-WITHDRAWAL SYMPTOMS (The Lancet, 1978)
- Agmatine: An endogenous clonidine-displacing substance in the brain (Science, 1994)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Clonidine
- Catapres
- Dixarit
- ST 155
- Catapresan
- Catapressan
- Gemiton
- Clofelin
- Clofenil
- M 5041T
- Hemiton
- ST155
- M-5041T
- Isoglaucon
- Klofelin
- Clopheline
- Clonidine Dihydrochloride
- M5041T
- Clonidine Monohydrochloride
- Boehringer Ingelheim Brand of Clonidine Hydrochloride
- Chlophazolin
- Klofenil
- ST-155
- Clonidine Monohydrobromide
-
SMILESC1CN=C(N1)NC2=C(C=CC=C2Cl)Cl.Cl
-
InChIKeyZNIFSRGNXRYGHF-UHFFFAOYSA-N
- Pubchem - CLONIDINE HYDROCHLORIDE
- Wikipedia - clonidine hydrochloride
Clonidine (trade names Catapres, Kapvay, Nexiclon, Clophelin, and others) is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, menopausal flushing, diarrhea, and certain pain conditions. It is classified as a centrally acting 2 adrenergic agonist and imidazoline receptor agonist that has been in clinical use since 1966.
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Synthesis
39075-79-1
+
Reactant
(Alkylation of primary amines)
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CLONIDINE HYDROCHLORIDE
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