| Weight | 323.465 g/mol |
|---|---|
| Formula | C19H21N3S |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
Cyamemazine (3546-03-0)
cyamamazine · 10-(3-dimethylamino-2-methylpropyl)phenothiazine-2-carbonitrile · cyamepromazine
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- Cyamemazine as an anxiolytic drug on the elevated plus maze and light/dark paradigm in mice (Behavioural Brain Research, 2001)
- Contrasting action of flavonoids on phototoxic effects induced in human skin fibroblasts by UVA alone or UVA plus cyamemazine, a phototoxic neuroleptic. (Photochemical and Photobiological Sciences, 2005)
- Cyamemazine decreases ethanol intake in rats and convulsions during ethanol withdrawal syndrome in mice (Psychopharmacology, 1998)
- Affinity of cyamemazine, an anxiolytic antipsychotic drug, for human recombinant dopamine vs. serotonin receptor subtypes (Biochemical Pharmacology, 2003)
- Preclinical and Clinical Pharmacology of Cyamemazine: Anxiolytic Effects and Prevention of Alcohol and Benzodiazepine Withdrawal Syndrome (Cns Drug Reviews, 2006)
- Effects of cyamemazine on herg, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs (European Journal of Pharmacology, 2006)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - cyamamazine
- 10-(3-dimethylamino-2-methylpropyl)phenothiazine-2-carbonitrile
- cyamepromazine
- cyamemazine monohydrochloride
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- Pubchem - Cyamemazine
- Wikipedia - cyamemazine
Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class which was introduced by Theraplix in France in 1972 and later in Portugal as well. It is used for the treatment of schizophrenia and, especially, for psychosis-associated anxiety, due to its unique anxiolytic efficacy. Cyamemazine differs from other phenothiazine neuroleptics in that aside from the usual profile of dopamine, 1-adrenergic, H1, and mACh receptor antagonism, it additionally produces potent blockade of several serotonin receptors, including 5-HT2A, 5-HT2C, and 5-HT7.
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