| Weight | 1202.635 g/mol |
|---|---|
| Formula | C62H111N11O12 |
| Hydrogen Acceptors | 12 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 15 |
cyclosporin A (59865-13-3)
Cyclosporine · Cyclosporin · Cyclosporine A
Score:
#76 in Neuroscience
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#89 in Biochemistry
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#400 in Biology
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#417 in Chemistry
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- Sigma-Aldrich - Search for cyclosporin A
- Fisher Scientific - Search for cyclosporin A
- TCI - Search for cyclosporin A
- Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes (Cell, 1991)
- The mechanism of action of cyclosporin A and FK506 (Immunology Today, 1992)
- The mechanism of action of cyclosporin A and FK506. (Clinical Immunology and Immunopathology, 1996)
- Cyclosporine in severe ulcerative colitis refractory to steroid therapy. (The New England Journal of Medicine, 1994)
- Cyclophilin: a specific cytosolic binding protein for cyclosporin A (Science, 1984)
- Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia (The New England Journal of Medicine, 1986)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - H302: Harmful if swallowed
Warning Acute toxicity, oral - Category 4 - H360: May damage fertility or the unborn child
Danger Reproductive toxicity - Category 1A, 1B - H372: Causes damage to organs through prolonged or repeated exposure
Danger Specific target organ toxicity, repeated exposure - Category 1 - Cyclosporine
- Cyclosporin
- Cyclosporine A
- Sandimmune
- Neoral
- Ciclosporin
- Sandimmun
- Sandimmun Neoral
- CsANeoral
- CyA-NOF
- CsA-Neoral
- CsA Neoral
- OL 27-400
- OL 27 400
- OL 27400
- CyA NOF
-
SMILESCCC1C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)CC=CC)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C
-
InChIKeyPMATZTZNYRCHOR-UHFFFAOYSA-N
- Pubchem - cyclosporin A
- Wikipedia - cyclosporine
Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product. It is used by mouth and injection into a vein for rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, and in organ transplants to prevent rejection. It is also used as eye drops for keratoconjunctivitis sicca (dry eyes).
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