| Weight | 105.093 g/mol |
|---|---|
| Formula | C3H7NO3 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 2 |
D-serine (312-84-5)
Score:
#561 in Neuroscience
,
#958 in Biochemistry
,
#2532 in Biology
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#3154 in Chemistry
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- d-Serine is an endogenous ligand for the glycine site of the N-methyl-d-aspartate receptor (Proceedings of the National Academy of Sciences of the United States of America, 2000)
- Long-term potentiation depends on release of D-serine from astrocytes. (Nature, 2010)
- D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. (Proceedings of the National Academy of Sciences of the United States of America, 1995)
- Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory (Cell, 2006)
- Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. (Proceedings of the National Academy of Sciences of the United States of America, 1999)
- D-serine added to antipsychotics for the treatment of schizophrenia (Biological Psychiatry, 1998)
-
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SMILESC(C(C(=O)O)N)O
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- Pubchem - D-serine
- Wikipedia - D-serine
Serine (abbreviated as Ser or S) encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an -amino acid that is used in the biosynthesis of proteins. It contains an -amino group (which is in the protonated NH+ 3 form under biological conditions), a carboxyl group (which is in the deprotonated COO form in physiological conditions), and a side chain consisting of a hydroxymethyl group (see hydroxyl), classifying it as a polar amino acid. It can be synthesized in the human body under normal physiological circumstances, making it a nonessential amino acid.
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