| Weight | 309.453 g/mol |
|---|---|
| Formula | C21H27NO |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
Difenidol (972-02-1)
diphenidol · Vontrol · diphenidol hydrochloride
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- p-fluoro-hexahydro-sila-difenidol: The first M2-selective muscarinic antagonist (European Journal of Pharmacology, 1988)
- Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes (European Journal of Pharmacology, 1989)
- Pharmacology of hexahydro-difenidol, hexahydro-sila-difenidol and related selective muscarinic antagonists. (Trends in Pharmacological Sciences, 1989)
- Binding and functional properties of antimuscarinics of the hexocyclium/sila-hexocyclium and hexahydro-diphenidol/hexahydro-sila-diphenidol type to muscarinic receptor subtypes (British Journal of Pharmacology, 1989)
- Interaction of p-F-HHSiD (p-Fluoro-hexahydrosila-difenidol) at muscarinic receptors in guinea-pig trachea (Naunyn-schmiedebergs Archives of Pharmacology, 1990)
- Stereoselective interaction of procyclidine, hexahydro-difenidol, hexbutinol and oxyphencyclimine, and of related antagonists, with four muscarinic receptors (European Journal of Pharmacology, 1992)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - diphenidol
- Vontrol
- diphenidol hydrochloride
- Cephadol
- diphenidol pamoate
- diphenidol hydrochloride, alpha-(14)C-labeled
- Cryopharma brand of diphenidol hydrochloride
- SmithKline Beecham brand of diphenidol hydrochloride
- GlaxoSmithKline brand of diphenidol hydrochloride
- Cefadol
- Normavom
-
SMILESC1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O
-
InChIKeyOGAKLTJNUQRZJU-UHFFFAOYSA-N
- Pubchem - Difenidol
- Wikipedia - diphenidol
Diphenidol is a muscarinic antagonist employed as an antiemetic and as an antivertigo agent. It is not marketed in the United States or Canada. - Although the mechanism of action of Diphenidol on the vestibular system has not yet been elucidated, it exerts an anticholinergic effect due to interactions with mACh receptors, particularly M1, M2, M3 and M4.
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