| Weight | 114.104 g/mol |
|---|---|
| Formula | C4H6N2O2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 0 |
dihydrouracil (504-07-4)
Score:
#1532 in Biochemistry
,
#4458 in Chemistry
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- Sigma-Aldrich - dihydrouracil152.00 USD
- Fisher Scientific - Search for dihydrouracil
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- Correlation Between Uracil and Dihydrouracil Plasma Ratio, Fluorouracil (5-FU) Pharmacokinetic Parameters, and Tolerance in Patients With Advanced Colorectal Cancer: A Potential Interest for Predicting 5-FU Toxicity and Determining Optimal 5-FU Dosage (Journal of Clinical Oncology, 1999)
- Distribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrate. (Anticancer Research, 1986)
- Mercury binding to nucleic acids. Crystal and molecular structures of 2:1 complexes of uracil-mercuric chloride and dihydrouracil-mercuric chloride. (Biochemistry, 1971)
- Dihydrouracil Dehydrogenase Activity in Normal, Differentiating, and Regenerating Liver and in Hepatomas (Cancer Research, 1971)
- Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients. (Clinical Cancer Research, 2000)
- The Uracil Breath Test in the Assessment of Dihydropyrimidine Dehydrogenase Activity: Pharmacokinetic Relationship between Expired 13CO2 and Plasma [2-13C]Dihydrouracil (Clinical Cancer Research, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CNC(=O)NC1=O
-
InChIKeyOIVLITBTBDPEFK-UHFFFAOYSA-N
- Pubchem - dihydrouracil
- Wikipedia - dihydrouracil
Dihydrouracil is an intermediate in the catabolism of uracil.
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Synthesis
Reactant
+
dimethyl sulfide
(Corey-Kim oxidation of secondary alcohols)
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dihydrouracil
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