| Weight | 292.426 g/mol |
|---|---|
| Formula | C20H24N2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 5 |
DIMETHINDENE (5636-83-9)
Forhistal · Dimethindene Maleate · Dimethpyrindene
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- Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene. (British Journal of Pharmacology, 1991)
- Comparative capillary electrophoresis and NMR studies of enantioseparation of dimethindene with cyclodextrins (Journal of Chromatography A, 1998)
- Mechanistic study of opposite migration order of dimethindene enantiomers in capillary electrophoresis in the presence of native -cyclodextrin and heptakis(2,3,6-tri-O-methyl)--cyclodextrin (Journal of Chromatography A, 2000)
- Simultaneous enantioselective determination and quantification of dimethindene and its metabolite N-demethyl-dimethindene in human urine using cyclodextrins as chiral additives in capillary electrophoresis (Journal of Pharmaceutical and Biomedical Analysis, 1994)
- Analytical method for simultaneously measuring ex vivo drug receptor occupancy and dissociation rate: application to (R)-dimethindene occupancy of central histamine H1 receptors. (Journal of Receptors and Signal Transduction, 2009)
- Cutaneous responses to substance P and calcitonin generelated peptide in chronic urticaria: the effect of cetirizine and dimethindene (Allergy, 1999)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Forhistal
- Dimethindene Maleate
- Dimethpyrindene
- Fenistil
- Novartis Brand of Dimethindene Maleate
- Dimetindene
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SMILESCC(C1=CC=CC=N1)C2=C(CC3=CC=CC=C32)CCN(C)C
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InChIKeyMVMQESMQSYOVGV-UHFFFAOYSA-N
- Pubchem - DIMETHINDENE
- Wikipedia - dimethindene
Dimetindene (trade name Fenistil; other name dimethindene maleate) is an antiallergic drug. Dimetindene is an antihistamine/anticholinergic that is a selective H1 antagonist. As dimetindene only minimally passes across the blood-brain barrier, it is classified as a second generation antihistamine.
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