| Weight | 297.423 g/mol |
|---|---|
| Formula | C18H19NOS |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 6 |
duloxetine (116539-59-4, 136434-34-9)
Score:
#200 in Neuroscience
,
#935 in Biology
,
#1034 in Chemistry
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- Duloxetine vs. placebo in patients with painful diabetic neuropathy. (Pain, 2005)
- A doubleblind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder (Arthritis & Rheumatism, 2004)
- Comparative Affinity of Duloxetine and Venlafaxine for Serotonin and Norepinephrine Transporters in vitro and in vivo, Human Serotonin Receptor Subtypes, and Other Neuronal Receptors (Neuropsychopharmacology, 2001)
- A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral neuropathic pain. (Pain Medicine, 2005)
- A randomized, double-blind, placebo-controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder (Pain, 2005)
- A randomized controlled trial of duloxetine in diabetic peripheral neuropathic pain (Neurology, 2006)
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SMILESCNCCC(C1=CC=CS1)OC2=CC=CC3=CC=CC=C32
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- Pubchem - duloxetine
- Wikipedia - duloxetine
Duloxetine, sold under the brand name Cymbalta among others, is a medication mostly used for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. It is a thiophene derivative and a selective neurotransmitter reuptake inhibitor for serotonin, norepinephrine, and to a lesser degree dopamine. It belongs to a class of heterocyclic antidepressants known as serotoninnorepinephrine reuptake inhibitors (SNRIs).
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