| Weight | 341.407 g/mol |
|---|---|
| Formula | C20H23NO4 |
| Hydrogen Acceptors | 3 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 6 |
Efaproxiral (131179-95-8)
"What do you need help with?"
LabBot
- Sigma-Aldrich - Search for Efaproxiral
- Fisher Scientific - Search for Efaproxiral
- TCI - Search for Efaproxiral
- Phase III Study of Efaproxiral As an Adjunct to Whole-Brain Radiation Therapy for Brain Metastases (Journal of Clinical Oncology, 2006)
- Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral (Chemical Communications, 2008)
- Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral (Efaproxyn) plus whole-brain radiation therapy for brain metastases. (American Journal of Clinical Oncology, 2007)
- Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival (International Journal of Radiation Oncology Biology Physics, 2006)
- Efaproxiral: a novel radiation sensitiser (Expert Opinion on Investigational Drugs, 2004)
- The effects of efaproxyn (Efaproxiral) on subcutaneous RIF-1 tumor oxygenation and enhancement of radiotherapy-mediated inhibition of tumor growth in mice (Radiation Research, 2007)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC(=CC(=C1)NC(=O)CC2=CC=C(C=C2)OC(C)(C)C(=O)O)C
-
InChIKeyBNFRJXLZYUTIII-UHFFFAOYSA-N
- Pubchem - Efaproxiral
- Wikipedia - efaproxiral
Efaproxiral (INN) is an analogue of the cholesterol drug bezafibrate developed for the treatment of depression, traumatic brain injury, ischemia, stroke, myocardial infarction, diabetes, hypoxia, sickle cell disease, hypercholesterolemia and as a radio sensitiser. The chemical is a propanoic acid in the class of amphipathic carboxylic acids. Most propanoic acid produced is consumed as a preservative for both animal feed and food for human consumption.
Suppliers
Most-cited Publications
Areas of Application
Safety
Alternate Names
External Links
Synthesis
2-methyl-2-phenoxypropanoic acid
+
2-chloro-N-(3,5-dimethylphenyl)acetamide
(Friedel-Crafts alkylation)
Reactant
+
3,5-Dimethylaniline
(Schotten-Baumann amide from acid)
Similar Compounds
Phenmedipham
(13684-63-4)
1 alternate name
3 safety hazards
3 suppliers
Tebufenpyrad
(119168-77-3)
1 alternate name
8 safety hazards
3 suppliers
XIPAMIDE
(14293-44-8)
1 alternate name
3 suppliers
Pyrinuron
(53558-25-1)
1 alternate name
1 safety hazard
3 suppliers
Tri-m-tolyl phosphate
(563-04-2)
1 alternate name
3 suppliers
lonidamine
(50264-69-2)
1 alternate name
3 suppliers
methoxychlor
(72-43-5)
1 alternate name
3 safety hazards
3 suppliers
DICOFOL
(115-32-2)
1 alternate name
6 safety hazards
3 suppliers
TRI-P-CRESYL PHOSPHATE
(78-32-0, 1330-78-5)
1 alternate name
3 safety hazards
3 suppliers
BENZILIC ACID
(76-93-7)
1 alternate name
1 safety hazard
3 suppliers
Orphenadrine hydrochloride
(341-69-5)
1 alternate name
3 suppliers
Cefadroxil monohydrate
(66592-87-8)
1 alternate name
3 suppliers
Assert
(69969-22-8)
1 alternate name
3 suppliers
3'-Methyl-4-dimethylaminoazobenzene
(55-80-1)
1 alternate name
3 suppliers
Quinizarin
(81-64-1, 86321-26-8)
1 alternate name
1 safety hazard
3 suppliers
3,5-Diiodothyronine
(534-51-0, 1041-01-6, 5563-89-3)
1 alternate name
3 suppliers
2-(Benzoylamino)benzoic acid
(579-93-1)
1 alternate name
3 suppliers
Cridanimod
(38609-97-1)
1 alternate name
3 suppliers
Fenpropimorph
(67564-91-4)
1 alternate name
2 safety hazards
3 suppliers
Clofenotane
(50-29-3)
1 alternate name
4 safety hazards
3 suppliers
TRI-O-CRESYL PHOSPHATE
(78-30-8)
1 alternate name
1 safety hazard
3 suppliers
p,p'-DDD
(72-54-8)
1 alternate name
3 suppliers
CINERIN II
(121-20-0)
1 alternate name
2 safety hazards
3 suppliers
sulfometuron-methyl
(74222-97-2)
1 alternate name
3 safety hazards
3 suppliers
Imazapic
(104098-48-8)
1 alternate name
3 suppliers
Ethylan
(72-56-0)
1 alternate name
3 suppliers
DIMETHRIN
(70-38-2)
1 alternate name
3 suppliers
Diphenyl p-tolyl phosphate
(78-31-9)
1 alternate name
3 suppliers
119-47-1
(119-47-1)
1 alternate name
3 suppliers
Clofencet
(129025-54-3)
1 alternate name
3 suppliers
79-97-0
(79-97-0)
1 alternate name
3 suppliers
FENARIMOL
(60168-88-9)
1 alternate name
4 safety hazards
3 suppliers
Chrysophanol
(481-74-3)
1 alternate name
3 suppliers
Progabide
(62666-20-0)
1 alternate name
3 suppliers
Progabide
(62666-20-0, 104880-78-6)
1 alternate name
3 suppliers
Metamizol
(50567-35-6)
1 alternate name
3 suppliers
Progabide
(62666-20-0)
1 alternate name
3 suppliers
Phthalyl-DL-glutamic Acid
(2301-52-2, 6349-98-0)
1 alternate name
3 suppliers
UNII-FY74W1G2FI
(4128-73-8)
1 alternate name
3 suppliers
AMITRAZ
(33089-61-1)
1 alternate name
5 safety hazards
3 suppliers
TRIPHENYL PHOSPHATE
(115-86-6)
1 alternate name
1 safety hazard
3 suppliers
Cephalexin hydrate
(15686-71-2, 23325-78-2)
1 alternate name
3 suppliers
IMAZETHAPYR
(81335-77-5)
1 alternate name
3 suppliers
Bisphenol AF
(1478-61-1)
1 alternate name
3 suppliers
TCSA
(1154-59-2)
1 alternate name
3 suppliers
CAS Directory
