| Weight | 631.666 g/mol |
|---|---|
| Formula | C34H38N3O7P |
| Hydrogen Acceptors | 9 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 10 |
Efonidipine (111011-63-3)
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- Effects of efonidipine on platelet and monocyte activation markers in hypertensive patients with and without type 2 diabetes mellitus (Journal of Human Hypertension, 2002)
- Inhibition of myocardial L- and T-type Ca2+ currents by efonidipine: possible mechanism for its chronotropic effect (European Journal of Pharmacology, 1998)
- Spectroscopic studies on the interaction of efonidipine with bovine serum albumin (Brazilian Journal of Medical and Biological Research, 2008)
- Protective Effects of Efonidipine, a T- and L-Type Calcium Channel Blocker, on Renal Function and Arterial Stiffness in Type 2 Diabetic Patients with Hypertension and Nephropathy (Journal of Atherosclerosis and Thrombosis, 2009)
- Identification of R()-isomer of efonidipine as a selective blocker of T-type Ca2+ channels (British Journal of Pharmacology, 2004)
- Effects of Ca2+ channel antagonists on sinus node: Prolongation of late phase 4 depolarization by efonidipine (European Journal of Pharmacology, 1997)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5
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InChIKeyNSVFSAJIGAJDMR-UHFFFAOYSA-N
- Pubchem - Efonidipine
- Wikipedia - efonidipine
Efonidipine (INN) is a dihydropyridine calcium channel blocker marketed by Shionogi & Co. of Japan. It was launched in 1995, under the brand name Landel ().
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