Weight | 307.478 g/mol |
---|---|
Formula | C19H33NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 3 |
Aromatic Rings | 1 |
Rotatable Bonds | 12 |
Fingolimod (162359-55-9)
Score:
#126 in Neurology
,
#572 in Neuroscience
,
#2578 in Biology
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- A Placebo-Controlled Trial of Oral Fingolimod in Relapsing Multiple Sclerosis (The New England Journal of Medicine, 2010)
- Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis (The New England Journal of Medicine, 2010)
- Oral Fingolimod (FTY720) for Relapsing Multiple Sclerosis (The New England Journal of Medicine, 2006)
- Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis (Nature Reviews Drug Discovery, 2010)
- Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis (Clinical Neuropharmacology, 2010)
- FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation (Proceedings of the National Academy of Sciences of the United States of America, 2011)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N
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- Pubchem - Fingolimod
- Wikipedia - fingolimod
Fingolimod (INN, trade name Gilenya, Novartis) is an immunomodulating drug, mostly used for treating multiple sclerosis (MS). It has reduced the rate of relapses in relapsing-remitting multiple sclerosis by approximately one-half over a two-year period. Fingolimod is a sphingosine-1-phosphate receptor modulator, which sequesters lymphocytes in lymph nodes, preventing them from contributing to an autoimmune reaction.
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