Weight | 410.507 g/mol |
---|---|
Formula | C22H34O7 |
Hydrogen Acceptors | 7 |
Hydrogen Donors | 3 |
Aromatic Rings | 0 |
Rotatable Bonds | 2 |
forskolin
NKH-477 · NKH 477 · NKH477
66575-29-9, 64657-11-0, 66428-89-5
Score:
#766 in Neuroscience
,
#1411 in Biochemistry
,
#3375 in Biology
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#4203 in Chemistry
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- Sigma-Aldrich - forskolin184.50 - 708.00 USD
- Fisher Scientific - Search for forskolin
- TCI - forskolin108.00 - 378.00 USD
- Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. (Journal of Biological Chemistry, 1990)
- Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells (Proceedings of the National Academy of Sciences of the United States of America, 1981)
- Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein. (Journal of Biological Chemistry, 1981)
- Forskolin: a unique diterpene activator of cyclic AMP-generating systems. (Journal of cyclic nucleotide research, 1981)
- Forskolin: its biological and chemical properties. (Advances in cyclic nucleotide and protein phosphorylation research, 1986)
- Characterization of the 5-hydroxytryptamine1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes (Journal of Pharmacology and Experimental Therapeutics, 1986)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - NKH-477
- NKH 477
- NKH477
- Coleonol
- colforsin
- N,N-dimethyl-beta-alanine-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho(2,1-b)pyran-6-yl ester HCl
-
SMILESCC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O
-
InChIKeyOHCQJHSOBUTRHG-UHFFFAOYSA-N
- Pubchem - forskolin
- Wikipedia - forskolin
Forskolin (coleonol) is a labdane diterpene that is produced by the Indian Coleus plant (Plectranthus barbatus). Other names include pashanabhedi, Indian coleus, makandi, HL-362, NKH477, and mao hou qiao rui hua. As with other members of the large diterpene family of natural products, forskolin is derived from geranylgeranyl pyrophosphate (GGPP).
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