Weight | 450.988 g/mol |
---|---|
Formula | C22H27ClN2O4S |
Hydrogen Acceptors | 6 |
Hydrogen Donors | 0 |
Aromatic Rings | 2 |
Rotatable Bonds | 6 |
Diltiazem hydrochloride
Diltiazem · Cardizem · Dilacor
38411-61-9, 33286-22-5, 8059-38-9
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- Sigma-Aldrich - Diltiazem hydrochloride25.50 - 540.00 USD
- Fisher Scientific - Search for Diltiazem hydrochloride
- TCI - Diltiazem hydrochloride75.00 - 231.00 USD
- Randomised trial of effects of calcium antagonists compared with diuretics and -blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study (The Lancet, 2000)
- Comparative pharmacology of calcium antagonists: Nifedipine, verapamil and diltiazem (American Journal of Cardiology, 1980)
- Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells. (Nature, 1983)
- Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. (JAMA, 2004)
- The effect of diltiazem on mortality and reinfarction after myocardial infarction (Journal of Emergency Medicine, 1989)
- Diltiazem and Reinfarction in Patients with Non-Q-Wave Myocardial Infarction (The New England Journal of Medicine, 1986)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Diltiazem
- Cardizem
- Dilacor
- Tiazac
- Dilacor XR
- CRD401
- Aldizem
- CRD-401
- Cardil
- CRD 401
- Dilren
- Watson Pharmaceuticals Brand of Diltazem
- Biovail Brand of Diltiazem Hydrochloride
- Diltiazem Malate
- Dilzem
-
SMILESCC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl
-
InChIKeyHDRXZJPWHTXQRI-UHFFFAOYSA-N
- Pubchem - Diltiazem hydrochloride
- Wikipedia - diltiazem hydrochloride
Diltiazem (INN) () is a nondihydropyridine (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia. It relaxes the smooth muscles in the walls of arteries, which opens (dilates) the arteries, allows blood to flow more easily, and lowers blood pressure. Additionally, it lowers blood pressure by acting on the heart itself to reduce the rate, strength, and conduction speed of each beat.
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