| Weight | 217.268 g/mol |
|---|---|
| Formula | C13H15NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
glutethimide (77-21-4)
Doriden · Noxiron
Score:
#1199 in Biology
,
#1375 in Chemistry
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- Effects of Amino-glutethimide on Adrenal Function in Man1 (The Journal of Clinical Endocrinology and Metabolism, 1967)
- Solubilizing Properties of Bile Salt Solutions I: Effect of Temperature and Bile Salt Concentration on Solubilization of Glutethimide, Griseofulvin, and Hexestrol (Journal of Pharmaceutical Sciences, 1966)
- Successful medical adrenalectomy with amino-glutethimide. Role of altered drug metabolism. (JAMA, 1974)
- The effects of phenobarbital, chloral betaine, and glutethimide administration on warfarin plasma levels and hypoprothrombinemic responese in man. (Clinical Pharmacology & Therapeutics, 1969)
- Solubilizing properties of bile salt solutions II. Effect of inorganic electrolyte, lipids, and a mixed bile salt system on solubilization of glutethimide, griseofulvin, and hexestrol (Journal of Pharmaceutical Sciences, 1966)
- Acute glutethimide intoxication: I. Clinical experience (twenty-two patients) compared to acute barbiturate intoxication (sixty-three patients) (The American Journal of Medicine, 1962)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Doriden
- Noxiron
-
SMILESCCC1(CCC(=O)NC1=O)C2=CC=CC=C2
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InChIKeyJMBQKKAJIKAWKF-UHFFFAOYSA-N
- Pubchem - glutethimide
- Wikipedia - glutethimide
Glutethimide is a hypnotic sedative that was introduced by Ciba in 1954 as a safe alternative to barbiturates to treat insomnia. Before long, however, it had become clear that glutethimide was just as likely to cause addiction and caused similarly severe withdrawal symptoms. Doriden was the brand-name version of the drug; it was also available under the brand names Elrodorm, Noxyron, Glimid and others.
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