hydroxybupropion (92264-81-8, 82793-84-8)

"What do you need help with?"

LabBot

Procurement
Synthesis
Safety
Alternatives
Testing
Regulation
Thanks, you'll receive a follow-up email shortly!

Suppliers

• Sigma-Aldrich - Search for hydroxybupropion
• Fisher Scientific - Search for hydroxybupropion
• TCI - Search for hydroxybupropion

Safety

• Request a Demo
  Predict GHS Hazards for Any Chemical in silico.
  Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.

Alternate Names

• 4-hydroxy bupropion
• SMILES
  CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)CO
• InChIKey
  AKOAEVOSDHIVFX-UHFFFAOYSA-N

External Links

• Pubchem - hydroxybupropion
• Wikipedia - (+/-)-hydroxybupropion
  Hydroxybupropion (code name BW 306U), or 6-hydroxybupropion, is the major active metabolite of the antidepressant and smoking cessation drug bupropion. It is formed from bupropion by the liver enzyme CYP2B6 during first-pass metabolism. With oral bupropion treatment, hydroxybupropion is present in plasma at area under the curve concentrations that are as many as 1620 times greater than those of bupropion itself, demonstrating extensive conversion of bupropion into hydroxybupropion in humans.

Synthesis

2-Amino-2-methyl-1-propanol  +  34841-41-3 (Alkylation of primary amines)

AC1MHK2A  +  dimethyl sulfide (Corey-Kim oxidation of secondary alcohols)

CHLOROBENZENE  +  Reactant (Friedel-Crafts acylation)

Reactant  +  1,3-DICHLOROBENZENE (Grignard carbonyl)

Synthesis of hydroxybupropion ›

Similar Compounds

Bupropion hydrochloride (34841-36-6, 31677-93-7)

2 alternate names

3 suppliers

2,4-Di-tert-butylphenol (96-76-4)

2 alternate names

4 safety hazards

3 suppliers

2,6-DI-TERT-BUTYLPHENOL (128-39-2)

2 alternate names

3 suppliers

LINURON (330-55-2)

2 alternate names

4 safety hazards

3 suppliers

2094-99-7 (2094-99-7)

2 alternate names

4 safety hazards

3 suppliers

Terbuthylazine (5915-41-3)

2 alternate names

3 suppliers

BUTACARB (2655-19-8)

2 alternate names

3 suppliers

2,5-Di-tert-amylhydroquinone (79-74-3)

2 alternate names

3 suppliers

1,3-DIISOPROPYLBENZENE (99-62-7)

2 alternate names

1 safety hazard

3 suppliers

2',3',4'-TRICHLOROACETOPHENONE (13608-87-2)

2 alternate names

3 suppliers

propanil (709-98-8)

2 alternate names

3 safety hazards

3 suppliers

DIETHYL PHTHALATE (68988-18-1, 84-66-2)

2 alternate names

3 safety hazards

3 suppliers

propazine (139-40-2)

2 alternate names

2 safety hazards

3 suppliers

Fenoprop (93-72-1)

2 alternate names

4 safety hazards

3 suppliers

CYANAZINE (21725-46-2)

2 alternate names

4 safety hazards

3 suppliers

FORMETANATE HYDROCHLORIDE (23422-53-9)

2 alternate names

5 safety hazards

3 suppliers

CHLORBROMURON (13360-45-7)

2 alternate names

3 suppliers

FORMETANATE (22259-30-9)

2 alternate names

3 safety hazards

3 suppliers

CHLORAZINE (580-48-3)

2 alternate names

3 suppliers

719-22-2 (719-22-2)

2 alternate names

3 suppliers

DIMETHYL ISOPHTHALATE (1459-93-4)

2 alternate names

3 suppliers

2-tert-Butyl-4-methylphenol (2409-55-4)

2 alternate names

2 safety hazards

3 suppliers

ERBON (136-25-4)

2 alternate names

1 safety hazard

3 suppliers

101-96-2 (101-96-2)

2 alternate names

3 suppliers

ISOPROTURON (34123-59-6)

2 alternate names

2 safety hazards

3 suppliers

4-tert-Butylcyclohexyl acetate (10411-92-4, 1900-69-2, 32210-23-4)

2 alternate names

3 suppliers

2,5-Di-tert-butyl-1,4-benzoquinone (2460-77-7)

2 alternate names

3 suppliers

Monoethyl phthalate (2306-33-4)

2 alternate names

3 suppliers

Pseudoephedrine Hcl (345-78-8)

2 alternate names

3 suppliers

2-Acetamidofluorene (53-96-3)

2 alternate names

3 suppliers

CHLORDIMEFORM (6164-98-3)

2 alternate names

7 safety hazards

3 suppliers

DIISOBUTYL PHTHALATE (84-69-5)

2 alternate names

3 safety hazards

3 suppliers

Crufomate (299-86-5)

2 alternate names

6 safety hazards

3 suppliers

DEXFENFLURAMINE HYDROCHLORIDE (3239-45-0, 3239-44-9)

2 alternate names

3 suppliers

m-Cumenyl methylcarbamate (64-00-6)

2 alternate names

3 suppliers

MONOLINURON (1746-81-2)

2 alternate names

3 safety hazards

3 suppliers

ethoxyquin (63301-91-7, 91-53-2)

2 alternate names

4 safety hazards

3 suppliers

SWEP (1918-18-9)

2 alternate names

1 safety hazard

3 suppliers

1,2-DIISOPROPYLBENZENE (577-55-9, 25321-09-9)

2 alternate names

2 safety hazards

3 suppliers

ISOPROPYLBIPHENYL (19486-60-3, 25640-78-2)

2 alternate names

3 suppliers

3006-86-8 (3006-86-8)

2 alternate names

3 suppliers

Compound 5353 (2282-34-0)

2 alternate names

3 suppliers

DESMEDIPHAM (13684-56-5)

2 alternate names

4 safety hazards

3 suppliers

Ionone, methyl- (127-42-4, 7779-30-8, 93302-56-8, 1335-46-2)

2 alternate names

3 suppliers

Damascenone (23696-85-7, 23726-93-4)

2 alternate names

3 suppliers

M-(1-ETHYLPROPYL)PHENYL METHYLCARBAMATE (672-04-8)

2 alternate names

3 suppliers

Thbp (1421-63-2)

2 alternate names

3 suppliers

71868-10-5 (71868-10-5)

2 alternate names

1 safety hazard

3 suppliers

1,4-DIISOPROPYLBENZENE (100-18-5)

2 alternate names

3 suppliers

Dipropyl phthalate (131-16-8)

2 alternate names

3 suppliers

p-Phenylacetanilide (4075-79-0)

2 alternate names

3 suppliers

6-tert-Butyl-m-cresol (88-60-8)

2 alternate names

5 safety hazards

3 suppliers

beta-Damascone (639-99-6, 23726-91-2, 35044-68-9, 23726-91-2)

2 alternate names

3 suppliers

Thiacetazone (104-06-3)

2 alternate names

3 suppliers

dibutyl phthalate (84-74-2)

2 alternate names

3 safety hazards

3 suppliers

Dimethyl phthalate (131-11-3)

2 alternate names

5 safety hazards

3 suppliers

MECOPROP (93-65-2, 7085-19-0)

2 alternate names

4 safety hazards

3 suppliers

diuron (330-54-1)

2 alternate names

5 safety hazards

3 suppliers

Ephedrine sulphate (134-72-5)

2 alternate names

3 suppliers

propachlor (1918-16-7)

2 alternate names

3 safety hazards

3 suppliers

prometryn (7287-19-6)

2 alternate names

3 suppliers

PHENTHOATE (2597-03-7, 61391-87-5, 61361-99-7, 61362-00-3)

2 alternate names

6 safety hazards

3 suppliers

prometon (1610-18-0)

2 alternate names

3 suppliers

DIMETHYL TEREPHTHALATE (120-61-6)

2 alternate names

2 safety hazards

3 suppliers

Edifenphos (17109-49-8)

2 alternate names

7 safety hazards

3 suppliers

Selegiline hydrochloride (14611-52-0)

2 alternate names

3 suppliers

FLUOMETURON (2164-17-2)

2 alternate names

3 suppliers

Butylate (2008-41-5)

2 alternate names

3 suppliers

Krzewotoks (93-79-8)

2 alternate names

3 suppliers

DIALLYL PHTHALATE (131-17-9)

2 alternate names

4 safety hazards

3 suppliers

4-tert-Butyltoluene (98-51-1)

2 alternate names

1 safety hazard

3 suppliers

DIPHENAMID (957-51-7)

2 alternate names

1 safety hazard

3 suppliers

17298-37-2 (17298-37-2)

2 alternate names

3 suppliers

Guanabenz acetate (23256-50-0)

2 alternate names

3 suppliers

BIS(2-METHOXYETHYL) PHTHALATE (117-82-8)

2 alternate names

1 safety hazard

3 suppliers

NOOTKATONE (4674-50-4, 28834-25-5)

2 alternate names

3 suppliers

Show More

• Account Setup
• Social Profiles
• Personal Details

Which industry is this for?

• Research
• Manufacturing
• CRO / CMO
• Pharmaceuticals
• Government / Regulation
• Services

What is your zip code / postal code?

We'll find the best matches for your location.

Finding the Best Matches

Where should we send your matches?