Weight | 425.613 g/mol |
---|---|
Formula | C27H39NO3 |
Hydrogen Acceptors | 4 |
Hydrogen Donors | 2 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
JERVINE (469-59-0)
jervine, acetate, (3beta,23beta)-isomer
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- Sigma-Aldrich - JERVINE143.50 USD
- Fisher Scientific - Search for JERVINE
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- Cyclopamine and jervine in embryonic rat tongue cultures demonstrate a role for Shh signaling in taste papilla development and patterning : fungiform papillae double in number and form in novel locations in dorsal lingual epithelium (Developmental Biology, 2003)
- Teratogenic effects of cyclopamine and jervine in rats, mice and hamsters. (Experimental Biology and Medicine, 1975)
- The Structure of Jervine. III. Degradation to Nitrogen-free Derivatives (Journal of the American Chemical Society, 1953)
- Veratrum alkaloids. LIV. Stereochemistry of jervine and related alkaloids (Journal of the American Chemical Society, 1968)
- C-Nor-D-homosteroids and related alkaloids. IX. Synthesis of jervine and related alkaloids (Journal of the American Chemical Society, 1967)
- Structure-activity relation of steroid teratogens. I. Jervine ring system. (Journal of Agricultural and Food Chemistry, 1978)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - jervine, acetate, (3beta,23beta)-isomer
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SMILESCC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5C(=O)C4=C3C)C)O)C)NC1
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InChIKeyCLEXYFLHGFJONT-UHFFFAOYSA-N
- Pubchem - JERVINE
- Wikipedia - jervine
Jervine is a steroidal alkaloid with molecular formula C27H39NO3 which is derived from the Veratrum plant genus. Similar to cyclopamine, which also occurs in the Veratrum genus, it is a teratogen implicated in birth defects when consumed by animals during a certain period of their gestation.
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