| Weight | 232.192 g/mol |
|---|---|
| Formula | C8H12N2O6 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 5 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 1 |
kifunensine (109944-15-2)
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- Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I. (Journal of Biological Chemistry, 1990)
- Demonstration that a kifunensine-resistant alpha-mannosidase with a unique processing action on N-linked oligosaccharides occurs in rat liver endoplasmic reticulum and various cultured cells. (Journal of Biological Chemistry, 1993)
- Endoplasmic Reticulum Kifunensine-Resistant -Mannosidase Is Enzymatically and Immunologically Related to the Cytosolic -Mannosidase (Archives of Biochemistry and Biophysics, 1996)
- Microbial oxidation of aromatics in enantiocontrolled synthesis. 2. Rational design of aza sugars (endo-nitrogenous). Total synthesis of +-kifunensine, mannojirimycin, and other glycosidase inhibitors. (Journal of the American Chemical Society, 1994)
- A combined STD-NMR/molecular modeling protocol for predicting the binding modes of the glycosidase inhibitors kifunensine and salacinol to golgi -mannosidase II (Biochemistry, 2005)
- Structure of kifunensine, a new immunomodulator isolated from an actinomycete (Journal of Organic Chemistry, 1989)
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Predict GHS Hazards for Any Chemical in silico.
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SMILESC(C1C(C(C(C2N1C(=O)C(=O)N2)O)O)O)O
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InChIKeyOIURYJWYVIAOCW-UHFFFAOYSA-N
- Pubchem - kifunensine
- Wikipedia - Kifunensine
Kifunensine is an alkaloid originally isolated from Kitasatosporia kifunense, an actinobacterium (formerly called an actinomycete). It is a neutral, stable compound. Kifunensine is a potent inhibitor of the mannosidase I enzyme and is primarily used in cell culture to make high mannose glycoproteins.
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kifunensine
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