Weight | 256.096 g/mol |
---|---|
Formula | C9H7Cl2N5 |
Hydrogen Acceptors | 5 |
Hydrogen Donors | 2 |
Aromatic Rings | 2 |
Rotatable Bonds | 1 |
lamotrigine (84057-84-1)
Lamictal · 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine · Labileno
Score:
#22 in Neurology
,
#109 in Neuroscience
,
#562 in Biology
,
#598 in Chemistry
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- A Double-Blind Placebo-Controlled Study of Lamotrigine Monotherapy in Outpatients With Bipolar I Depression (The Journal of Clinical Psychiatry, 1999)
- The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial (The Lancet, 2007)
- The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. (The Lancet, 2007)
- A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Manic or Hypomanic Patients With Bipolar I Disorder (Archives of General Psychiatry, 2003)
- Double-blind comparison of lamotrigine and carbamazepine in newly diagnosed epilepsy (The Lancet, 1995)
- Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action. (Epilepsia, 1986)
-
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Lamictal
- 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
- Labileno
- Crisomet
- BW-430C
- 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine
- Lamiktal
-
SMILESC1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
-
InChIKeyPYZRQGJRPPTADH-UHFFFAOYSA-N
- Pubchem - lamotrigine
- Wikipedia - lamotrigine
Lamotrigine, sold as the brandname Lamictal among other, is an anticonvulsant medication used to treat epilepsy and bipolar disorder. For epilepsy, this includes focal seizures, tonic-clonic seizures, and seizures in Lennox-Gastaut syndrome. In bipolar, it is used to treat acute episodes of depression, rapid cycling in bipolar type II, and prevent recurrence in bipolar type I.
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Estimated Properties
Boiling Point | 352.58 C | EPA T.E.S.T. |
---|---|---|
Density | 1.64 g/cm3 | EPA T.E.S.T. |
Flash Point | 280.55 C | EPA T.E.S.T. |
Water Solubility | 15.78 mg/L | EPA T.E.S.T. |
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