Weight | 342.479 g/mol |
---|---|
Formula | C22H30O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 0 |
Rotatable Bonds | 1 |
megestrol (3562-63-8)
Score:
#108 in Microbiology
,
#1185 in Biology
,
#1354 in Chemistry
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- Letrozole, a new oral aromatase inhibitor for advanced breast cancer : Double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate (Journal of Clinical Oncology, 1998)
- Exemestane Is Superior to Megestrol Acetate After Tamoxifen Failure in Postmenopausal Women With Advanced Breast Cancer: Results of a Phase III Randomized Double-Blind Trial (Journal of Clinical Oncology, 2000)
- Megestrol acetate for the prevention of hot flashes. (The New England Journal of Medicine, 1994)
- Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: Results of a survival update based on a combined analysis of data from two mature phase III trials (Cancer, 1998)
- Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. Arimidex Study Group. (Journal of Clinical Oncology, 1996)
- Phase III, Multicenter, Double-Blind, Randomized Study of Letrozole, an Aromatase Inhibitor, for Advanced Breast Cancer Versus Megestrol Acetate (Journal of Clinical Oncology, 2001)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESCC1=CC2C(CCC3(C2CCC3(C(=O)C)O)C)C4(C1=CC(=O)CC4)C
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InChIKeyVXIMPSPISRVBPZ-UHFFFAOYSA-N
- Pubchem - megestrol
- Wikipedia - megestrol
Megestrol (INN, BAN) is a steroidal progestin of the 17-hydroxyprogesterone group which was never marketed and is not currently used clinically. Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.
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