| Weight | 203.241 g/mol |
|---|---|
| Formula | C12H13NO2 |
| Hydrogen Acceptors | 2 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 1 |
METHSUXIMIDE (77-41-8)
Celontin · Parke David brand of methsuximide · Petinutin
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- Influence of oxcarbazepine and methsuximide on lamotrigine concentrations in epileptic patients with and without valproic acid comedication: results of a retrospective study. (Therapeutic Drug Monitoring, 1999)
- Anticonvulsant activity and toxicity of phensuximide, methsuximide and ethosuximide. (Epilepsia, 1963)
- Plasma levels of methsuximide and Ndesmethylmethsuximide during methsuximide therapy (Neurology, 1974)
- Methsuximide lowers lamotrigine blood levels: A pharmacokinetic antiepileptic drug interaction. (Epilepsia, 2000)
- Charcoal Hemoperfusion in the Therapy for Methsuximide and Phenytoin Overdose (JAMA Internal Medicine, 1980)
- Celontin (PM-396) in the treatment of epilepsy. (Pediatrics, 1957)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Celontin
- Parke David brand of methsuximide
- Petinutin
- N,2-dimethyl-2-phenylsuccinimide
- Pfizer brand of methsuximide
- methsuximide, (+)-isomer
- mesuximide
- Warner-Lambert brand of methsuximide
- mesuximid
- methsuximide, (-)-isomer
- methsuximide, (+-)-isomer
-
SMILESCC1(CC(=O)N(C1=O)C)C2=CC=CC=C2
-
InChIKeyAJXPJJZHWIXJCJ-UHFFFAOYSA-N
- Pubchem - METHSUXIMIDE
- Wikipedia - methsuximide
Mesuximide (or methsuximide, methosuximide) is a succinimide anticonvulsant medication. It is sold as a racemate by Pfizer under the tradenames Petinutin (Switzerland) and Celontin (United States). The therapeutic efficacy of methosuximide is largely due to its pharmacologically active metabolite, N-desmethylmethosuximide, which has a longer half-life and attains much higher plasma levels than its parent.
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METHSUXIMIDE
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