| Weight | 353.466 g/mol |
|---|---|
| Formula | C21H27N3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
methysergide (361-37-5)
Sansert · Methysergide Maleate · Deseril
Score:
#62 in Neurology
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#306 in Neuroscience
,
#1371 in Biology
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- Fibrotic Disorders Associated with Methysergide Therapy for Headache (The New England Journal of Medicine, 1966)
- Free-choice responding for ethanol versus water in alcohol preferring (P) and unselected Wistar rats is differentially modified by naloxone, bromocriptine, and methysergide (Psychopharmacology, 1990)
- MORE ABOUT METHYSERGIDE. (The Lancet, 1964)
- Antagonism of stimulation-produced antinociception by intrathecal administration of methysergide or phentolamine (Brain Research, 1984)
- Letter: Methysergide and myoclonus. (The Lancet, 1975)
- Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat (Brain Research, 1985)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Sansert
- Methysergide Maleate
- Deseril
- UML 491
- Methylmethylergonovine
- Alliance Brand of Methysergide Maleate
- Novartis Brand of Methysergide Maleate
- UML-491
- Dsernil-Sandoz
- Dimethylergometrin
- Methysergide Dimaleate
- Desril
- Dsernil Sandoz
- UML491
-
SMILESCCC(CO)NC(=O)C1CN(C2CC3=CN(C4=CC=CC(=C34)C2=C1)C)C
-
InChIKeyKPJZHOPZRAFDTN-UHFFFAOYSA-N
- Pubchem - methysergide
- Wikipedia - methysergide
Methysergide (1-methyl-D-lysergic acid butanolamide or UML-491) also known as methysergide maleate, is an ergot derived prescription drug used for the prophylaxis of difficult to treat migraine and cluster headaches. Methysergide is no longer recommended as a first line treatment protocol by international headache societies, hospitals, and neurologists in private practice, for migraines or cluster headaches as side effects were first reported with long-term use in the late 1960's, and ergot based treatments fell out of favor for the treatment of migraines with the introduction of triptans in the 1980's.
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