| Weight | 353.466 g/mol |
|---|---|
| Formula | C21H27N3O2 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 2 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 4 |
methysergide (361-37-5)
Sansert · Methysergide Maleate · Deseril
Score:
#62 in Neurology
,
#306 in Neuroscience
,
#1371 in Biology
"What do you need help with?"
LabBot
Suppliers
- Sigma-Aldrich - Search for methysergide
- Fisher Scientific - Search for methysergide
- TCI - Search for methysergide
Most-cited Publications
- Fibrotic Disorders Associated with Methysergide Therapy for Headache (The New England Journal of Medicine, 1966)
- Free-choice responding for ethanol versus water in alcohol preferring (P) and unselected Wistar rats is differentially modified by naloxone, bromocriptine, and methysergide (Psychopharmacology, 1990)
- MORE ABOUT METHYSERGIDE. (The Lancet, 1964)
- Antagonism of stimulation-produced antinociception by intrathecal administration of methysergide or phentolamine (Brain Research, 1984)
- Letter: Methysergide and myoclonus. (The Lancet, 1975)
- Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat (Brain Research, 1985)
Areas of Application
Safety
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more.
Trends
Alternate Names
- Sansert
- Methysergide Maleate
- Deseril
- UML 491
- Methylmethylergonovine
- Alliance Brand of Methysergide Maleate
- Novartis Brand of Methysergide Maleate
- UML-491
- Dsernil-Sandoz
- Dimethylergometrin
- Methysergide Dimaleate
- Desril
- Dsernil Sandoz
- UML491
-
SMILESCCC(CO)NC(=O)C1CN(C2CC3=CN(C4=CC=CC(=C34)C2=C1)C)C
-
InChIKeyKPJZHOPZRAFDTN-UHFFFAOYSA-N
External Links
- Pubchem - methysergide
- Wikipedia - methysergide
Methysergide (1-methyl-D-lysergic acid butanolamide or UML-491) also known as methysergide maleate, is an ergot derived prescription drug used for the prophylaxis of difficult to treat migraine and cluster headaches. Methysergide is no longer recommended as a first line treatment protocol by international headache societies, hospitals, and neurologists in private practice, for migraines or cluster headaches as side effects were first reported with long-term use in the late 1960's, and ergot based treatments fell out of favor for the treatment of migraines with the introduction of triptans in the 1980's.
Similar Compounds
terguride
(37686-84-3)
15 alternate names
3 suppliers
Methylergonovine maleate
(57432-61-8)
15 alternate names
3 suppliers
Deoxycorticosterone acetate
(56-47-3)
15 alternate names
3 suppliers
Methoprene
(36557-27-4, 40596-69-8, 52020-07-2)
15 alternate names
3 suppliers
COUMATETRALYL
(5836-29-3)
15 alternate names
2 safety hazards
3 suppliers
Benzo[j]fluoranthene
(205-82-3)
15 alternate names
3 safety hazards
3 suppliers
Furathiocarb
(65907-30-4)
15 alternate names
7 safety hazards
3 suppliers
IPRODIONE
(36734-19-7)
15 alternate names
5 safety hazards
3 suppliers
Bifenazate
(149877-41-8)
15 alternate names
5 safety hazards
3 suppliers
Zoxamide
(156052-68-5)
15 alternate names
2 safety hazards
3 suppliers
Butyl phthalyl butyl glycolate
(85-70-1)
15 alternate names
3 suppliers
testosterone enanthate
(315-37-7)
15 alternate names
3 suppliers
Milnacipran hydrochloride
(101152-94-7)
15 alternate names
3 suppliers
retinal
(116-31-4)
15 alternate names
3 suppliers
9-cis-Retinal
(514-85-2)
15 alternate names
3 suppliers
roscovitine
(186692-46-6)
15 alternate names
3 suppliers
Benzyl butyl phthalate
(85-68-7)
15 alternate names
4 safety hazards
3 suppliers
Benz[a]anthracene
(56-55-3)
15 alternate names
4 safety hazards
3 suppliers
VINCLOZOLIN
(50471-44-8)
15 alternate names
3 safety hazards
3 suppliers
BENOMYL
(17804-35-2)
15 alternate names
7 safety hazards
3 suppliers
TRIMETHYLOLPROPANE TRIACRYLATE
(15625-89-5)
15 alternate names
2 safety hazards
3 suppliers
5-METHYLCHRYSENE
(3697-24-3)
15 alternate names
1 safety hazard
3 suppliers
Melsedin
(340-56-7, 2915-01-7)
15 alternate names
3 suppliers
Napropamide
(15299-99-7)
15 alternate names
3 suppliers
estradiol valerate
(979-32-8)
15 alternate names
3 suppliers
COUMAFURYL
(117-52-2)
15 alternate names
2 safety hazards
3 suppliers
Iofendylate
(99-79-6)
15 alternate names
3 suppliers
VALONE
(83-28-3)
15 alternate names
3 suppliers
2,7-DIMETHYLPYRENE
(15679-24-0)
15 alternate names
3 suppliers
Licarbazepine
(29331-92-8)
15 alternate names
3 suppliers
Dibenzepin
(4498-32-2)
15 alternate names
3 suppliers
DEHP
(15495-94-0, 8033-53-2, 117-81-7)
15 alternate names
6 safety hazards
3 suppliers
dibutyl phthalate
(84-74-2)
15 alternate names
3 safety hazards
3 suppliers
cypermethrin
(52315-07-8, 67375-30-8, 97955-44-7)
15 alternate names
11 safety hazards
3 suppliers
PROMETHAZINE HYDROCHLORIDE
(58-33-3)
15 alternate names
3 suppliers
TRIADIMEFON
(43121-43-3)
15 alternate names
2 safety hazards
3 suppliers
CAS Directory
