| Weight | 219.281 g/mol |
|---|---|
| Formula | C10H21NO4 |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 4 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 4 |
Miglustat (72599-27-0)
Score:
#125 in Neurology
,
#567 in Neuroscience
,
#2562 in Biology
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- Sigma-Aldrich - Miglustat100.00 - 296.00 USD
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- Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study (Lancet Neurology, 2007)
- The role of the iminosugar N-butyldeoxynojirimycin (miglustat) in the management of type I (non-neuronopathic) Gaucher disease: A position statement (Journal of Inherited Metabolic Disease, 2003)
- Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease (Journal of Inherited Metabolic Disease, 2004)
- Randomized, controlled trial of miglustat in Gaucher's disease type 3. (Annals of Neurology, 2008)
- Rescue of functional delF508-CFTR channels in cystic fibrosis epithelial cells by the -glucosidase inhibitor miglustat (FEBS Letters, 2006)
- Miglustat in adult and juvenile patients with NiemannPick disease type C: Long-term data from a clinical trial (Molecular Genetics and Metabolism, 2010)
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SMILESCCCCN1CC(C(C(C1CO)O)O)O
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InChIKeyUQRORFVVSGFNRO-UHFFFAOYSA-N
- Pubchem - Miglustat
- Wikipedia - miglustat
Miglustat (OGT 918, N-butyl-deoxynojirimycin) is a drug developed by Oxford GlycoSciences and marketed by Actelion and is used primarily to treat type I Gaucher disease (GD1). It is marketed under the trade name Zavesca.
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Miglustat
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