Weight | 224.985 g/mol |
---|---|
Formula | C4H4INO2 |
Hydrogen Acceptors | 2 |
Hydrogen Donors | 0 |
Aromatic Rings | 0 |
Rotatable Bonds | 0 |
N-Iodosuccinimide (516-12-1)
Score:
#2696 in Biochemistry
,
#6681 in Chemistry
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- Synthetic methods and reactions. 181. Iodination of deactivated aromatics with N-iodosuccinimide in trifluoromethanesulfonic acid (NIS-CF3SO3H) via in situ generated superelectrophilic iodine(I) trifluoromethanesulfonate (Journal of Organic Chemistry, 1993)
- Mild and regioselective iodination of electron-rich aromatics with N-iodosuccinimide and catalytic trifluoroacetic acid (Tetrahedron Letters, 2002)
- Iodonium ion generated in situ from N-iodosuccinimide and trifluoromethanesulphonic acid promotes direct linkage of disarmed pent-4-enyl glycosides (Journal of The Chemical Society, Chemical Communications, 1990)
- Halogenation of Aromatic Compounds by N-chloro-, N-bromo-, and N-iodosuccinimide (Chemistry Letters, 2003)
- The N-iodosuccinimide-mediated conversion of aldehydes to methyl esters (Journal of Organic Chemistry, 1989)
- Mild and regiospecific nuclear iodination of methoxybenzenes and naphthalenes with N-iodosuccinimide in acetonitrile (Tetrahedron Letters, 1996)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CC(=O)N(C1=O)I
-
InChIKeyLQZMLBORDGWNPD-UHFFFAOYSA-N
- Pubchem - N-Iodosuccinimide
- Wikipedia - N-iodosuccinimide
N-Iodosuccinimide (NIS) is a reagent used in organic chemistry for the iodination of alkenes and as a mild oxidant. NIS is the iodine analog of N-chlorosuccinimide (NCS) and N-bromosuccinimide (NBS) which are used for similar applications.
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