| Weight | 293.37 g/mol |
|---|---|
| Formula | C18H19N3O |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 3 |
| Rotatable Bonds | 2 |
ondansetron (99614-01-4, 99614-02-5)
Zofran · Ondansetron Hydrochloride · GR38032F
Score:
#31 in Neurology
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#149 in Neuroscience
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#736 in Biology
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#800 in Chemistry
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- Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron (Annals of Oncology, 2003)
- Efficacy, dose-response, and safety of ondansetron in prevention of postoperative nausea and vomiting, A quantitative systematic review of randomized placebo-controlled trials (Anesthesiology, 1997)
- Efficacy of ondansetron (GR 38032F) and the role of serotonin in cisplatin induced nausea and vomiting (The New England Journal of Medicine, 1990)
- Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial. (JAMA, 2000)
- Comparison of the 5-Hydroxytryptamine3 (Serotonin) Antagonist Ondansetron (Gr 38032F) with High-Dose Metoclopramide in the Control of Cisplatin-Induced Emesis (The New England Journal of Medicine, 1990)
- A phase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy (Annals of Oncology, 2006)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Zofran
- Ondansetron Hydrochloride
- GR38032F
- GR 38032F
- Ondansetron Monohydrochloride
- GR-38032F
- SN307
- Ondansetron, (R)-Isomer
- SN-307
- Ondansetron, (+,-)-Isomer
- Ondansetron Monohydrochloride Dihydrate
- Ondansetron, (S)-Isomer
- SN 307
-
SMILESCC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
-
InChIKeyFELGMEQIXOGIFQ-UHFFFAOYSA-N
- Pubchem - ondansetron
- Wikipedia - ondansetron
Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. It is also useful in gastroenteritis. It has little effect on vomiting caused by motion sickness.
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Estimated Properties
| Boiling Point | 384.03 C | EPA T.E.S.T. |
|---|---|---|
| Density | 1.24 g/cm3 | EPA T.E.S.T. |
| Flash Point | 257.23 C | EPA T.E.S.T. |
| Water Solubility | 15.81 mg/L | EPA T.E.S.T. |
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ondansetron
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