Weight | 313.441 g/mol |
---|---|
Formula | C20H27NO2 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 2 |
Aromatic Rings | 1 |
Rotatable Bonds | 2 |
Oxilorphan (42281-59-4)
oxilorphan hydrochloride, (9alpha,13alpha,14alpha)-isomer · oxilorphan, (14alpha)-(+-)-isomer · L-N-cyclopropylmethyl-3,14-dihydroxymorphinan
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - oxilorphan hydrochloride, (9alpha,13alpha,14alpha)-isomer
- oxilorphan, (14alpha)-(+-)-isomer
- L-N-cyclopropylmethyl-3,14-dihydroxymorphinan
- oxilorphan tartrate (2:1), (R-(R*,R*))-isomer
- oxilorphan hydrochloride
- oxilorphan, (+-)-isomer
- oxilorphan tartrate, (R-(R*,R*))-isomer
- oxilorphan hydrochloride, (+-)-isomer
- oxilorphan, (14alpha)-isomer
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SMILESC1CCC2(C3CC4=C(C2(C1)CCN3CC5CC5)C=C(C=C4)O)O
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InChIKeySTBZIDOIKQNFCQ-UHFFFAOYSA-N
- Pubchem - Oxilorphan
- Wikipedia - oxilorphan
Oxilorphan (INN, USAN) (developmental code name L-BC-2605) is an opioid antagonist of the morphinan family that was never marketed. It acts as a -opioid receptor (MOR) antagonist but a -opioid receptor (KOR) partial agonist, and has similar effects to naloxone and around the same potency as an MOR antagonist. Oxilorphan has some weak partial agonist actions at the MOR (with miosis, nausea, dizziness, and some euphoria observed) and can produce hallucinogenic/dissociative effects at sufficient doses, indicative of KOR activation.
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