Weight | 324.38 g/mol |
---|---|
Formula | C19H20N2O3 |
Hydrogen Acceptors | 3 |
Hydrogen Donors | 1 |
Aromatic Rings | 2 |
Rotatable Bonds | 5 |
oxyphenbutazone (129-20-4)
Tanderil · Oxyphenylbutazone · Hydroxyphenylbutazone
Score:
#925 in Biochemistry
,
#2451 in Biology
,
#3053 in Chemistry
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- Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone. (European Journal of Pharmacology, 1973)
- Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone. (BMJ, 1977)
- The measurement of binding constants using circular dichroism: Binding of phenylbutazone and oxyphenbutazone (Biochemical Pharmacology, 1970)
- Simultaneous determination of hydrocortisone, dexamethasone, indomethacin, phenylbutazone and oxyphenbutazone in equine serum by high-performance liquid chromatography (Journal of Chromatography B: Biomedical Sciences and Applications, 2000)
- Phenylbutazone and oxyphenbutazone distribution into tissue fluids in the horse (Journal of Veterinary Pharmacology and Therapeutics, 1986)
- A comparative study of the metabolism of desmethylimipramine, nortriptyline, and oxyphenylbutazone in man. (Clinical Pharmacology & Therapeutics, 1969)
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Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Tanderil
- Oxyphenylbutazone
- Hydroxyphenylbutazone
- Belmac Brand of Oxyphenbutazone
- Novartis Ophthalmics Brand of Oxyphenbutazone
- Diflamil
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SMILESCCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
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InChIKeyHFHZKZSRXITVMK-UHFFFAOYSA-N
- Pubchem - oxyphenbutazone
- Wikipedia - oxyphenbutazone anhydrous
Oxyphenbutazone is a nonsteroidal anti-inflammatory drug (NSAID). It is a metabolite of phenylbutazone. It was withdrawn from markets worldwide in mid-1980s due to bone marrow suppression and StevensJohnson syndrome.
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