| Weight | 243.394 g/mol |
|---|---|
| Formula | C17H25N |
| Hydrogen Acceptors | 1 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 1 |
| Rotatable Bonds | 2 |
PHENCYCLIDINE (77-10-1)
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#177 in Neuroscience
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- Recent advances in the phencyclidine model of schizophrenia. (American Journal of Psychiatry, 1991)
- The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate (British Journal of Pharmacology, 1983)
- Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs (Science, 1989)
- The Neuropsychopharmacology of Phencyclidine: From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia (Neuropsychopharmacology, 1999)
- Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats (Science, 1998)
- Amphetamine, cocaine, phencyclidine and nomifensine increase extracellular dopamine concentrations preferentially in the nucleus accumbens of freely moving rats (Neuroscience, 1989)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. -
SMILESC1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3
-
InChIKeyJTJMJGYZQZDUJJ-UHFFFAOYSA-N
- Pubchem - PHENCYCLIDINE
- Wikipedia - phencyclidine
Phencyclidine (PCP), also known as angel dust among other names, is a dissociative drug. PCP was brought to market in the 1950s as an anesthetic pharmaceutical drug but was taken off the market in 1965 due to the high prevalence of dissociative hallucinogenic side effects. Moreover, the discovery of ketamine by Parke-Davis researchers was thought to represent a better-tolerated alternative for use as an anesthetic medication.
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PHENCYCLIDINE
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