| Weight | 356.447 g/mol |
|---|---|
| Formula | C19H20N2O3S |
| Hydrogen Acceptors | 5 |
| Hydrogen Donors | 1 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 7 |
Pioglitazone (111025-46-8)
Actos · pioglitazone hydrochloride · U72,107A
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#194 in Neuroscience
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#907 in Biology
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#1003 in Chemistry
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- Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial (The Lancet, 2005)
- Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis (The New England Journal of Medicine, 2010)
- A Placebo-Controlled Trial of Pioglitazone in Subjects with Nonalcoholic Steatohepatitis (The New England Journal of Medicine, 2006)
- Pioglitazone and Risk of Cardiovascular Events in Patients With Type 2 Diabetes Mellitus: A Meta-analysis of Randomized Trials (JAMA, 2007)
- A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia (Diabetes Care, 2005)
- A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis (Hepatology, 2004)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - Actos
- pioglitazone hydrochloride
- U72,107A
- U 72107A
- AD-4833
- U-72107A
- AD 4833
- 5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
-
SMILESCCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
-
InChIKeyHYAFETHFCAUJAY-UHFFFAOYSA-N
- Pubchem - Pioglitazone
- Wikipedia - pioglitazone
Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results. Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events.
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Pioglitazone
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