| Weight | 298.346 g/mol |
|---|---|
| Formula | C16H18N4O2 |
| Hydrogen Acceptors | 6 |
| Hydrogen Donors | 0 |
| Aromatic Rings | 2 |
| Rotatable Bonds | 3 |
piribedil (3605-01-4)
ET 495 · Trivastal · Piribedil Mesylate
Score:
#206 in Neurology
,
#914 in Neuroscience
,
#4021 in Biology
,
#5064 in Chemistry
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- Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys (Pharmacology, Biochemistry and Behavior, 1986)
- Effects of a dopamine agonist piribedil in depressed patients: relationship of pretreatment homovanillic acid to antidepressant response. (Archives of General Psychiatry, 1978)
- Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil (Brain, 2013)
- Cholinergic-dopaminergic interaction in the striatum: The effect of 6-hydroxydopamine or pimozide treatment on the increased striatal acetylcholine levels induced by apomorphine, piribedil andD-amphetamine (Brain Research, 1975)
- Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity. (Advances in Neurology, 1975)
- Effects of -cyclodextrins on skin: implications for the transdermal delivery of piribedil and a novel cognition enhancing-drug, S-9977 (European Journal of Pharmaceutical Sciences, 1995)
-
Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - ET 495
- Trivastal
- Piribedil Mesylate
- EU-4200
- Piribedil Hydrochloride
- EU 4200
- Piribedil Mono-hydrochloride
- ET495
- ET-495
- EU4200
- Piribedil Mono hydrochloride
- Piribendyl
-
SMILESC1CN(CCN1CC2=CC3=C(C=C2)OCO3)C4=NC=CC=N4
-
InChIKeyOQDPVLVUJFGPGQ-UHFFFAOYSA-N
- Pubchem - piribedil
- Wikipedia - piribedil
Piribedil (trade names Pronoran, Trivastal Retard, Trastal, Trivastan, Clarium and others) is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist. It also has 2-adrenergic antagonist properties.
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piribedil
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