| Weight | 352.471 g/mol |
|---|---|
| Formula | C20H32O5 |
| Hydrogen Acceptors | 4 |
| Hydrogen Donors | 3 |
| Aromatic Rings | 0 |
| Rotatable Bonds | 12 |
Prostaglandin E2 (363-24-6)
PGE2 · Dinoprostone · Prepidil Gel
Score:
#312 in Neuroscience
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#415 in Biochemistry
,
#1407 in Biology
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#1647 in Chemistry
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- Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF. (Journal of Clinical Investigation, 1998)
- Modulation of Apoptosis and Bcl-2 Expression by Prostaglandin E2 in Human Colon Cancer Cells (Cancer Research, 1998)
- Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. (Journal of Experimental Medicine, 1985)
- Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. (Journal of Biological Chemistry, 2000)
- IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. (Proceedings of the National Academy of Sciences of the United States of America, 1988)
- Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis (Nature, 2007)
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Predict GHS Hazards for Any Chemical in silico.
Including Acute Oral Tox, Skin Sensitization, Eye Irritation, Aquatic Tox, & more. - PGE2
- Dinoprostone
- Prepidil Gel
- PGE2alpha
- PGE2 alpha
- Prostaglandin E2alpha
- Prostaglandin E2 alpha
- Prostenon
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SMILESCCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
-
InChIKeyXEYBRNLFEZDVAW-UHFFFAOYSA-N
- Pubchem - Prostaglandin E2
- Wikipedia - dinoprostone
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin which is used as a medication. As a medication it is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open. In babies it is used in those with congenital heart defects until surgery can be carried out.
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